Transforming growth factor-β mediates loss of epidermal integrity and melanoma ulceration

被引:0
|
作者
Ellis, R. [1 ]
Verykiou, S. [3 ]
Anagnostou, M. [3 ]
Hill, D. [3 ]
Carling, E. [2 ]
Lovat, P. [3 ]
机构
[1] James Cook Univ Hosp, Dept Dermatol, Middlesbrough, Cleveland, England
[2] James Cook Univ Hosp, Dept Pathol, Middlesbrough, Cleveland, England
[3] Newcastle Univ, Dept Dermatol Sci, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
O13
引用
收藏
页码:E44 / E45
页数:2
相关论文
共 50 条
  • [1] Melanoma secretion of transforming growth factor-beta 2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration
    Cosgarea, I
    McConnell, A. T.
    Ewen, T.
    Tang, D.
    Hill, D. S.
    Anagnostou, M.
    Elias, M.
    Ellis, R. A.
    Murray, A.
    Spender, L. C.
    Giglio, P.
    Gagliardi, M.
    Greenwood, A.
    Piacentini, M.
    Inman, G. J.
    Fimia, G. M.
    Corazzari, M.
    Armstrong, J. L.
    Lovat, P. E.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2022, 186 (04) : 694 - 704
  • [2] Loss of epidermal integrity and tumour ulceration in melanoma is driven by tumoral transforming growth factor-β2 secretion and mediated through AMBRA1 and claudin-1 downregulation
    Cosgarea, I.
    McConnell, A.
    Ewen, T.
    Tang, D.
    Greenwood, A.
    Armstrong, J.
    Lovat, P.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2022, 187 (01) : E2 - E2
  • [3] Melanoma transforming growth factor-β2 secretion leads to loss of endothelial integrity and tumour metastasis
    McConnell, A.
    Cosgarea, I.
    Shekleton, F.
    Murry, A.
    Ellis, R.
    Tang, D.
    Labus, M.
    Corazzari, M.
    Armstrong, J.
    Lovat, P.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2019, 180 (06) : E197 - E198
  • [4] Transforming growth factor-β-mediated Ambra-1 downregulation in melanoma ulceration and metastasis
    Ellis, R.
    Anagnostou, M. -E.
    Verykiou, S.
    Elias, M.
    Horswell, S.
    Kirkham, N.
    Lovat, P.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2014, 170 (04) : E28 - E28
  • [5] Transforming growth factor-β in cutaneous melanoma
    Javelaud, Delphine
    Alexaki, Vasileia-Ismini
    Mauviel, Alain
    [J]. PIGMENT CELL & MELANOMA RESEARCH, 2008, 21 (02) : 123 - 132
  • [6] Epidermal melanoma prognostic factors: a link to paracrine transforming growth factor-β signalling
    Paragh, Gyorgy
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2022, 186 (04) : 606 - 607
  • [8] Epidermal growth factor and transforming growth factor-α in middle ear effusion
    Nassif, PS
    Simpson, SQ
    Izzo, AA
    Nicklaus, PJ
    [J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1998, 119 (06) : 564 - 568
  • [9] Melanoma secretion of TGFβ2 mediates epidermal AMBRA1 and Claudin1 downregulation, loss of epidermal integrity and tumour ulceration
    Cosgarea, I.
    Mc Connell, A.
    Tang, D.
    Greenwood, A.
    Ellis, R.
    Lovat, P.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 139 (09) : S299 - S299
  • [10] Expression and localization of epidermal growth factor, transforming growth factor-α and epidermal growth factor receptor in the canine testis
    Tamada, Hiromichi
    Takemoto, Kohei
    Tominaga, Masato
    Kawate, Noritoshi
    Takahashi, Masahiro
    Hatoya, Shingo
    Matsuyama, Satoshi
    Inaba, Toshio
    Sawada, Tsutomu
    [J]. JOURNAL OF REPRODUCTION AND DEVELOPMENT, 2016, 62 (01): : 59 - 64