Kaposiform Hemangioendothelioma with Kasabach-Merritt Phenomenon: Successful Treatment with Embolization and Vincristine in Two Newborns

被引：34

作者：

Garcia-Monaco, Ricardo ^{[1
,2
]}

Giachetti, Ana ^{[1
]}

Peralta, Oscar ^{[1
,2
]}

Napoli, Noelia ^{[1
]}

Lobos, Pablo ^{[1
]}

Gioseffi, Laura

Mariani, Gonzalo

机构：

[1] Univ Buenos Aires, Vasc Anomalies Ctr, Dept Intervent Radiol, Hosp Italiano, RA-1053 Buenos Aires, DF, Argentina

[2] Univ Buenos Aires, Dept Pediat, Hosp Italiano, RA-1053 Buenos Aires, DF, Argentina

来源：

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY | 2012年 / 23卷 / 03期

关键词：

INFANTILE HEMANGIOMA; MANAGEMENT; THERAPY;

D O I：

10.1016/j.jvir.2011.12.007

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor and has a high mortality in newborns when associated with Kasabach-Merritt syndrome (KMS). In two newborns with KEE and severe KMS refractory to medical treatment, emergency embolization led to clinical improvement in the acute neonatal setting by reducing tumor volume, increasing the platelet count, and improving other clotting parameters. Systemic vincristine treatment was added for further tumor control. Both patients remained symptom-free at long-term follow-up.

引用

页码：417 / 422

页数：6

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