Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic

被引:18
|
作者
Asdaq, Syed Mohammed Basheeruddin [1 ]
Ikbal, Abu Md Ashif [2 ]
Sahu, Ram Kumar [3 ,4 ]
Bhattacharjee, Bedanta [5 ]
Paul, Tirna [5 ]
Deka, Bhargab [5 ]
Fattepur, Santosh [6 ]
Widyowati, Retno [3 ]
Vijaya, Joshi [7 ]
Al Mohaini, Mohammed [8 ,9 ]
Alsalman, Abdulkhaliq J. [10 ]
Imran, Mohd [11 ]
Nagaraja, Sreeharsha [12 ,13 ]
Nair, Anroop B. [12 ]
Attimarad, Mahesh [12 ]
Venugopala, Katharigatta N. [12 ,14 ]
机构
[1] AlMaarefa Univ, Coll Pharm, Dept Pharm Practice, Riyadh 13713, Saudi Arabia
[2] Tripura Univ, Dept Pharm, Suryamaninagar 799022, Tripura W, India
[3] Univ Airlangga, Fac Pharm, Dept Pharmaceut Sci, Surabaya 60115, Indonesia
[4] Assam Univ, Dept Pharmaceut Sci, Silchar 788011, Assam, India
[5] Dibrugarh Univ, Fac Sci & Engn, Dept Pharmaceut Sci, Dibrugarh 786004, Assam, India
[6] Management & Sci Univ, Sch Pharm, Seksyen 13, Shah Alam 40100, Selangor, Malaysia
[7] Govt Coll Pharm, Dept Pharmaceut, Bangalore 560027, Karnataka, India
[8] King Saud bin Abdulaziz Univ Hlth Sci, Coll Appl Med Sci, Basic Sci Dept, Alahsa 31982, Saudi Arabia
[9] King Abdullah Int Med Res Ctr, Alahsa 31982, Saudi Arabia
[10] Northern Border Univ, Fac Pharm, Dept Clin Pharm, Rafha 91911, Saudi Arabia
[11] Northern Border Univ, Fac Pharm, Dept Pharmaceut Chem, Rafha 91911, Saudi Arabia
[12] King Faisal Univ, Coll Clin Pharm, Dept Pharmaceut Sci, Al Hufuf 31982, Al Ahsa, Saudi Arabia
[13] Vidya Siri Coll Pharm, Dept Pharmaceut, Off Sarjapura Rd, Bangalore 560035, Karnataka, India
[14] Durban Univ Technol, Dept Biotechnol & Food Technol, ZA-4001 Durban, South Africa
关键词
COVID-19; nanotechnology; vaccines; sanitizers; biosensors; ACUTE RESPIRATORY SYNDROME; MEDIATED ISOTHERMAL AMPLIFICATION; HEPATITIS-B; SILVER NANOPARTICLES; INFLUENZA-VIRUS; CORONAVIRUS; DELIVERY; VACCINE; PROTEIN; REPLICATION;
D O I
10.3390/nano11071841
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus's basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.
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页数:27
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