Should people with chronic liver diseases be vaccinated against COVID-19?

被引:1
|
作者
Chen, Li-Ping [1 ]
Zeng, Qing-Hong [1 ]
Gong, Yuan-Feng [1 ,2 ]
Liang, Fa-Liang [1 ]
机构
[1] Xinxing Peoples Hosp, Dept Gen Surg, 2 Chengnanwai New Ave, Yunfu 527400, Guangdong, Peoples R China
[2] Guangzhou Med Univ, Dept Hepatobiliary Surg, Affiliated Canc Hosp & Inst, Guangzhou 510095, Guangdong, Peoples R China
关键词
Chronic liver disease; Vaccine; COVID-19; SARS-CoV-2; Hepatic impairment;
D O I
10.12998/wjcc.v9.i26.7959
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hepatic impairment in coronavirus disease 2019 (COVID-19) may derive from cholangiocyte damage in the beginning, but not from direct infection of hepatocytes. Chronic liver disease patients co-infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited overexpression of angiotensin-converting enzyme 2 receptors and overwhelming cytokine storm. Consensus has been reached that we should encourage as many people as possible to be vaccinated in order to achieve herd immunity. SARS-CoV-2 vaccines can prevent or alleviate severe infection and cytokine storm. It is recommended that all adult patients with chronic liver diseases and liver transplant recipients should receive COVID-19 vaccines using the standard dose and schedule. Data is not yet sufficient to compare the efficacy of different types of vaccines used in chronic liver disease patients.
引用
收藏
页码:7959 / 7962
页数:4
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