Phytochemical investigation and antimicrobial activity of Psidium guajava']java L. leaves

被引:99
|
作者
Metwally, A. M. [1 ]
Omar, A. A. [1 ]
Harraz, F. M. [1 ]
El Sohafy, S. M. [1 ]
机构
[1] Univ Alexandria, Fac Pharm, Dept Pharmacognosy, Alexandria, Egypt
关键词
Antimicrobial activity; guava leaves; Psidium gua[!text type='java']java[!/text] L; quercetin glycosides; quercetin; quercetin-3-O-beta-D-arabinopyranoside; HISTAMINE-RELEASE; FLAVONOIDS; INHIBITION; QUERCETIN; EXTRACTS; CELLS;
D O I
10.4103/0973-1296.66939
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Psidium guajava L. leaves were subjected to extraction, fractionation and isolation of the flavonoidal compounds. Five flavonoidal compounds were isolated which are quercetin, quercetin-3-O-alpha-L-arabinofuranoside, quercetin-3-O-beta-D-arabinopyranoside, quercetin-3-O-beta-D-glucoside and quercetin-3-O-beta-D-galactoside. Quercetin-3-O-beta-D-arabinopyranoside was isolated for the first time from the leaves. Fractions together with the isolates were tested for their antimicrobial activity. The antimicrobial studies showed good activities for the extracts and the isolated compounds.
引用
收藏
页码:212 / 218
页数:7
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