Studies towards the synthesis of guanidine alkaloids; Synthesis of a tricyclic guanidine from succinimide

被引：32
|
作者：
Louwrier, S [1 ]
Ostendorf, M [1 ]
Tuynman, A [1 ]
Hiemstra, H [1 ]
机构：
[1] UNIV AMSTERDAM, AMSTERDAM INST MOLEC STUDIES, ORGAN CHEM LAB, 1018 WS AMSTERDAM, NETHERLANDS
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 06期
关键词：
D O I：
10.1016/0040-4039(95)02258-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of a tricyclic guanidine as a model compound for ptilomycalin A and related guanidine alkaloids is described. The synthesis starts from succinimide and features an N-acyliminium ion coupling, an Eschenmoser sulfide-contraction and an N-guanylation as the key steps.
引用
收藏
页码：905 / 908
页数：4
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