Transpyloric feeding in premature infants with suspected gastroesophageal reflux associated apnea

In this study we investigated the role of transpyloric (TP) feeds in apnea of prematurity suspected to be due to gastroesophageal reflux Method: Retrospective chart review of premature infants on TP feed with documented apnea. Results:- Out of 32 eligible infants, 12 with documented apnea were included in the study. Though TP feeds significantly reduced (p <.05) the average apnea rate in the whole group, two infants did not show any reduction of number of apneas. The remaining 10 showed even stronger correlation between TP feeds and reduction of number of apneas. (p < .01). After discontinuation of TP feeds 1 required antireflux surgery, one was transferred to another hospital and 10 were discharged home. No TP tube related complication was documented. Conclusion:- The association between GER and apnea is difficult to establish even with sophisticated tests. In a properly selected population, TP feeds can be used for diagnosis and management of gastroesophageal reflux associated apnea.