Understanding High-Dose, Ultra-High Dose Rate, and Spatially Fractionated Radiation Therapy

被引：76

作者：

Griffin, Robert J. ^{[1
]}

Ahmed, Mansoor M. ^{[2
]}

Amendola, Beatriz ^{[3
]}

Belyakov, Oleg ^{[4
]}

Bentzen, Soren M. ^{[5
]}

Butterworth, Karl T. ^{[6
]}

Chang, Sha ^{[7
]}

Coleman, C. Norman ^{[2
]}

Djonov, Valentin ^{[8
]}

Formenti, Sylvia C. ^{[9
]}

Glatstein, Eli ^{[10
]}

Guha, Chandan ^{[11
]}

Kalnicki, Shalom ^{[11
]}

Le, Quynh-Thu ^{[12
]}

Loo, Billy W., Jr. ^{[12
]}

Mahadevan, Anand ^{[13
]}

Massaccesi, Mariangela ^{[14
]}

Maxim, Peter G. ^{[15
]}

Mohiuddin, Majid ^{[16
]}

Mohiuddin, Mohammed ^{[17
]}

Mayr, Nina A. ^{[18
]}

Obcemea, Ceferino ^{[2
]}

Petersson, Kristoffer ^{[19
]}

Regine, William ^{[20
]}

Roach, Mack ^{[21
]}

Romanelli, Pantaleo ^{[22
]}

Simone, Charles B., II ^{[23
]}

Snider, James W. ^{[20
]}

Spitz, Douglas R. ^{[24
]}

Vikram, Bhadrasain ^{[2
]}

Vozenin, Marie-Catherine ^{[25
]}

Abdel-Wahab, May ^{[26
]}

Welsh, James ^{[27
,28
]}

Wu, Xiaodong ^{[29
,30
]}

Limoli, Charles L. ^{[31
]}

机构：

[1] Univ Arkansas Med Sci, Dept Radiat Oncol, Little Rock, AR 72205 USA

[2] Div Canc Treatment & Diag, Rockville, MD USA

[3] Innovat Canc Inst, South Miami, FL USA

[4] IAEA, Vienna Int Ctr, Vienna, Austria

[5] Univ Maryland, Div Biostat & Bioinformat, Baltimore, MD 21201 USA

[6] Queens Univ Belfast, Ctr Canc Res & Cell Biol, Belfast, Antrim, North Ireland

[7] Univ N Carolina, Sch Med, Dept Radiat Oncol, Chapel Hill, NC 27515 USA

[8] Univ Bern, Bern Inst Anat, Bern, Switzerland

[9] Weill Cornell Med, Dept Radiat Oncol, New York, NY USA

[10] Univ Penn, Dept Radiat Oncol, Philadelphia, PA USA

[11] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Radiat Oncol, Bronx, NY 10467 USA

[12] Stanford Univ, Med Ctr, Dept Radiat Oncol, Stanford, CA 94305 USA

[13] Geisinger Hlth Syst, Dept Radiat Oncol, Danville, PA USA

[14] Fdn Policlin Univ A Gemelli IRCCS, Dept Radiat Oncol, Rome, Italy

[15] Indiana Univ Sch Med, Dept Radiat Oncol, Indianapolis, IN 46202 USA

[16] Radiat Oncol Consultants, Park Ridge, IL USA

[17] Radiat Oncol, Scottsdale, AZ USA

[18] Univ Washington, Med Ctr, Dept Radiat Oncol, Seattle, WA 98195 USA

[19] Univ Oxford, Oxford Inst Radiat Oncol, Oxford, England

[20] Univ Maryland, Sch Med, Dept Radiat Oncol, Baltimore, MD 21201 USA

[21] Univ Calif San Francisco, Dept Radiat Oncol & Urol, San Francisco, CA 94143 USA

[22] CDI, Cyberknife Ctr, Brain Radiosurg, Milan, Italy

[23] New York Proton Ctr, Dept Radiat Oncol, New York, NY USA

[24] Univ Iowa, Free Rad & Radiat Biol Program, Iowa City, IA USA

[25] Lausanne Univ Hosp, Lab Radiat Oncol DO Radiooncol CHUV, Lausanne, Switzerland

[26] Int Atom Energy Agcy Headquarters, Vienna Int Ctr, Vienna, Austria

[27] Edward Hines VA Med Ctr, Chicago, IL USA

[28] Loyola Univ, Stritch Sch Med, Chicago, IL 60611 USA

[29] Execut Med Phys Associates, Miami, FL USA

[30] Shanghai Proton & Heavy Ion Ctr, Shanghai, Peoples R China

[31] Univ Calif Irvine, Dept Radiat Oncol, Irvine, CA 92697 USA

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2020年 / 107卷 / 04期

关键词：

ELECTRON-BEAM DOSIMETRY; LUNG-CANCER; GRID BLOCK; RADIOTHERAPY; IRRADIATION; BRACHYTHERAPY; EFFICACY; CELLS; IMPLEMENTATION; RADIOSURGERY;

D O I：

10.1016/j.ijrobp.2020.03.028

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The National Cancer Institute's Radiation Research Program, in collaboration with the Radiosurgery Society, hosted a workshop called Understanding High-Dose, Ultra-High Dose Rate and Spatially Fractionated Radiotherapy on August 20 and 21, 2018 to bring together experts in experimental and clinical experience in these and related fields. Critically, the overall aims were to understand the biological underpinning of these emerging techniques and the technical/physical parameters that must be further defined to drive clinical practice through innovative biologically based clinical trials. (C) 2020 Elsevier Inc. All rights reserved.

引用

页码：766 / 778

页数：13

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