Selective Deficiency of Serine Arginine-Rich Splicing Factor 1 (SRSF1) in T Lymphocytes Leads to mTORC1 Activation, Treg Dysfunction and Systemic Autoimmune Disease

被引：0

作者：

Katsuyama, Takayuki ^{[1
]}

Li, Hao ^{[1
]}

Comte, Denis ^{[1
]}

Mosho, Michael W. ^{[2
]}

Gillooly, Andrew R. ^{[2
]}

Tsokos, George C. ^{[3
]}

Moulton, Vaishali R. ^{[1
]}

机构：

[1] Harvard Med Sch, Div Rheumatol, Dept Med, Beth Israel Deaconess Med Ctr, Boston, MA USA

[2] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Med Rheumatol, Boston, MA USA

[3] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Rheumatol, Boston, MA USA

来源：

ARTHRITIS & RHEUMATOLOGY | 2018年 / 70卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

936

引用

页数：2

共 50 条

[1] Serine/Arginine-Rich Splicing Factor 1 (SRSF1) Is a Novel Regulator of T Cell Function and Its Selective Deficiency in T Lymphocytes Leads to Autoimmunity and Lupus-like Nephritis
Moulton, Vaishali R.
Katsuyama, Takayuki
Li, Hao
Mosho, Michael W.
Gillooly, Andrew R.
Tsokos, George C.
[J]. ARTHRITIS & RHEUMATOLOGY, 2017, 69
[2] Serine Arginine-rich Splicing Factor 1 (SRSF1) Is Indispensable for Homeostasis and Function of Regulatory T Cells
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[J]. ARTHRITIS & RHEUMATOLOGY, 2019, 71
[3] Serine Arginine-Rich Splicing Factor 1 (SRSF1) Contributes to the Transcriptional Activation of CD3ζ in Human T Cells
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[J]. PLOS ONE, 2015, 10 (07):
[4] Serine Arginine-Rich Splicing Factor 1 (SRSF1) Is Essential for T Lymphocyte Homeostasis and Decreased Levels of SRSF1 Correlate with Lymphopenia in SLE Patients
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[J]. ARTHRITIS & RHEUMATOLOGY, 2018, 70
[5] Ubiquitination Regulates Expression of the Serine/Arginine-rich Splicing Factor 1 (SRSF1) in Normal and Systemic Lupus Erythematosus (SLE) T Cells
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Gillooly, Andrew R.
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[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (07) : 4126 - 4134
[6] Ubiquitination modulates expression of the serine arginine-rich splicing factor 1 (SRSF1) in activated T cells and in SLE patients
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[J]. JOURNAL OF IMMUNOLOGY, 2014, 192
[7] Estrogen Downregulates the Expression of Serine Arginine Splicing Factor 1 (SRSF1) in Human T Lymphocytes
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[J]. ARTHRITIS & RHEUMATOLOGY, 2017, 69
[8] Estrogen Controls the Expression of Serine Arginine-Rich Splicing Factor 1 (SRSF1) in Human T Lymphocytes Via Transcriptional and Post-Transcriptional Mechanisms
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[J]. ARTHRITIS & RHEUMATOLOGY, 2018, 70
[9] Serine Arginine-Rich Splicing Factor 1 (SRSF1) Is a Novel Regulator of T Lymphocyte Homeostasis In Vivo and Its Deficiency Associates with Lymphopenia in SLE Patients
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[J]. ARTHRITIS & RHEUMATOLOGY, 2017, 69
[10] Serine/Arginine-Rich Splicing Factor 1 (SRSF1) Is a Novel Factor in T Cell Homeostasis and Its Selective Loss in T Cells Causes Autoimmunity and Lupus-like Nephritis
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Mosho, Michael W.
Gillooly, Andrew R.
Keane, Meghan L.
Tsokos, George C.
[J]. ARTHRITIS & RHEUMATOLOGY, 2016, 68

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