Prevalence of Thyroid Disorders and Reference Range of Thyroid Hormones in Khartoum State, Sudan

Introduction: Thyroid hormones are the commonly used biochemical markers to diagnose thyroid malfunctions they are also been used to follow-up treatment specifically thyrotropin, total triiodothyronine, free triiodothyronine, total thyroxin and free thyroxin (TSH), (T3), (FT3), (T4) and (FT4) respectively. Objectives: The aim of this study is to calculate the Prevalence of thyroid disorders in Khartoum state and to relate them with, gender, age, and BMI, also to find the ratio of unforeseen thyroid hormonal function disorders in Khartoum and to initiate normal levels of thyroid related hormones Material and methods: Thyroid hormones were measured from 493 participants selected randomly to measure the prevalence of thyroid disorders and set a reference range for Khartoum state. Results: The overall prevalence of thyroid disorders were 120 (24.3%), 23.3% of them were hyperthyroidism and the rest 1% were hypothyroidism. The reference range for TSH, T3 and T4 were (0.10 mlU/L-5.60 mlU/L), (1.77 nmol/L-1.94 nmol/L), and (118.02 nmol/L-125.21 nmol/L) respectively. Conclusion: A Thyroid disorder in Khartoum State in Sudan was not uncommon, and was much lower than Darfur state. The reference range for thyroid hormones was different from other different studies.