CONDOP: an R package for CONdition-Dependent Operon Predictions

被引:4
|
作者
Fortino, Vittorio [1 ]
Tagliaferri, Roberto [2 ]
Greco, Dario [1 ]
机构
[1] Univ Helsinki, Inst Biotechnol, Helsinki, Finland
[2] Univ Salerno, NeuRoNe Lab, DISA MIS, Fisciano, Italy
基金
芬兰科学院;
关键词
D O I
10.1093/bioinformatics/btw330
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The use of high-throughput RNA sequencing to predict dynamic operon structures in prokaryotic genomes has recently gained popularity in bioinformatics. We provide the R implementation of a novel method that uses transcriptomic features extracted from RNA-seq transcriptome profiles to develop ensemble classifiers for condition-dependent operon predictions. The CONDOP package provides a deeper insight into RNA-seq data analysis and allows scientists to highlight the operon organization in the context of transcriptional regulation with a few lines of code.
引用
收藏
页码:3199 / 3200
页数:2
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