Survival Outcome Associated with the Screening Interval for Gastric Cancer in Korea

被引:25
|
作者
Lee, Hyuk [2 ]
Min, Byung-Hoon
Lee, Jun Haeng
Son, Hee Jung
Kim, Jae J.
Rhee, Jong Chul
Kim, Seonwoo [3 ]
Rhee, Poong-Lyul [1 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Div Gastroenterol, Samsung Med Ctr,Dept Med, Seoul 135710, South Korea
[2] Yonsei Univ, Coll Med, Dept Internal Med, Inst Gastroenterol, Seoul, South Korea
[3] Samsung Biomed Res Inst, Biostat Team, Seoul, South Korea
关键词
Stomach neoplasm; Screening; Survival; Metaplasia; INTESTINAL METAPLASIA; STOMACH-CANCER; EPIDEMIOLOGY; JAPAN;
D O I
10.1159/000326857
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background/Aims: Early gastric cancer (EGC) can be treated by endoscopic resection, which results in an excellent prognosis. Optimal screening intervals considering risk factors for gastric cancer have not been established. The aim of this study was to determine the maximum gastric cancer screening interval in terms of long-term survival. Methods: Curative resection was performed in 561 patients with gastric cancer who had completed a questionnaire on their previous history of screening tests and risk factors. The association between EGC detection rate and previous screening history was evaluated, and 5-year disease-free survival rates were compared between various screening intervals. Results: Multivariate analysis showed that intestinal metaplasia [hazard ratio (HR) 9.690, 95% confidence interval (CI) 5.896-15.927] and previous screening history (HR 0.077, 95% CI 0.048-0.125) were independent factors associated with advanced gastric cancer. In patients without intestinal metaplasia, there was no significant difference in the extent of gastric cancer progression and the 5-year disease-free survival rate between groups with screening intervals of less than 3 years. In patients with intestinal metaplasia, the cutoff screening interval for detection of EGC and disease-free survival was 2 years. Conclusion: The optimum screening interval for disease-free survival for gastric cancer in a normal population is 3 years, but a screening interval of 2 years should be used for patients with intestinal metaplasia in Korea. Copyright (C) 2011 S. Karger AG, Basel
引用
收藏
页码:142 / 148
页数:7
相关论文
共 50 条
  • [1] Survival Outcome Associated With Screening Intervals for Gastric Cancer in Korea
    Lee, Hyuk
    Kim, Jeong
    Min, Byung-Hoon
    Lee, Jun Haeng
    Kim, Jae J.
    Rhee, Jong Chul
    Rhee, Poong-Lyul
    [J]. GASTROENTEROLOGY, 2010, 138 (05) : S194 - S195
  • [2] Survival Analysis of Patients with Interval Cancer Undergoing Gastric Cancer Screening by Endoscopy
    Hamashima, Chisato
    Shabana, Michiko
    Okamoto, Mikizo
    Osaki, Yoneatsu
    Kishimoto, Takuji
    [J]. PLOS ONE, 2015, 10 (05):
  • [3] Factors associated with use of gastric cancer screening services in Korea
    Kwon, Young Min
    Lim, Hyung Taek
    Lee, Kiheon
    Cho, Be Long
    Park, Min Sun
    Son, Ki Young
    Park, Sang Min
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (29) : 3653 - 3659
  • [4] Factors associated with use of gastric cancer screening services in Korea
    Young Min Kwon
    Hyung Taek Lim
    Kiheon Lee
    Be Long Cho
    Min Sun Park
    Ki Young Son
    Sang Min Park
    [J]. World Journal of Gastroenterology, 2009, 15 (29) : 3653 - 3659
  • [5] Clinicopathologic Characteristics of Interval Gastric Cancer in Korea
    Park, Mi Sung
    Lee, Yong Chan
    Yoon, Ji Young
    Cheoi, Kyung Seok
    Park, Jun Chul
    Lee, Hyuk
    Shin, Sung Kwan
    Lee, Sang Kil
    [J]. GASTROINTESTINAL ENDOSCOPY, 2012, 75 (04) : 236 - 236
  • [6] Clinicopathologic Characteristics of Interval Gastric Cancer in Korea
    Park, Mi Sung
    Yoon, Ji Young
    Chung, Hyun Soo
    Lee, Hyuk
    Park, Jun Chul
    Shin, Sung Kwan
    Lee, Sang Kil
    Lee, Yong Chan
    [J]. GUT AND LIVER, 2015, 9 (02) : 167 - 173
  • [7] Epidemiology and screening of gastric cancer in Korea
    Song, Minkyo
    Lee, Hwi-Won
    Kang, Daehee
    [J]. JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, 2015, 58 (03): : 183 - 190
  • [8] Gastric Cancer Screening in Korea: Report on the National Cancer Screening Program in 2008
    Lee, Kyung Sook
    Oh, Dong Kwan
    Han, Mi Ah
    Lee, Hoo-Yeon
    Jun, Jae Kwan
    Choi, Kui Son
    Park, Eun-Cheol
    [J]. CANCER RESEARCH AND TREATMENT, 2011, 43 (02): : 83 - 88
  • [9] An Appropriate Interval in Performing Endoscopy Screening for Gastric Cancer
    Tsuji, Yosuke
    Ono, Akiko
    Ito, Takafumi
    Chiba, Hideyuki
    Ohata, Ken
    Gunji, Toshiaki
    Matsuhashi, Nobuyuki
    [J]. GASTROINTESTINAL ENDOSCOPY, 2012, 75 (04) : 156 - 157
  • [10] The Present Situation and Conditions of Gastric Cancer Screening in Korea
    Lee, Sang Pyo
    [J]. DIGESTION, 2020, 101 (01) : 85 - 86