Health-related quality of life predicts long-term survival in patients with peripheral artery disease

被引：46
|
作者：
Issa, Samson M. [2 ,3 ]
Hoeks, Sanne E. [4 ]
op Reimer, Wilma J. M. Scholte [5 ]
Van Gestel, Yvette R. B. M. [4 ]
Lenzen, Mattie J. [3 ]
Verhagen, Hence J. M. [1 ]
Pedersen, Susanne S. [2 ,3 ]
Poldermans, Don [1 ]
机构：
[1] Erasmus MC, Dept Vasc Surg, NL-3015 GD Rotterdam, Netherlands
[2] Tilburg Univ, CoRPS Ctr Res Psychol Somat Dis, NL-5000 LE Tilburg, Netherlands
[3] Erasmus MC, Thoraxctr, Dept Cardiol, NL-3015 GD Rotterdam, Netherlands
[4] Erasmus MC, Dept Anaesthesiol, NL-3015 GD Rotterdam, Netherlands
[5] Amsterdam Univ Appl Sci, Sch Nursing, Amsterdam, Netherlands
来源：
VASCULAR MEDICINE | 2010年 / 15卷 / 03期
关键词：
disease management; health-related quality of life; peripheral artery disease; prognosis; vascular surgery; MORTALITY; DEPRESSION; PROGNOSIS; OUTCOMES; RISK;
D O I：
10.1177/1358863X10364208
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
We examined whether health-related quality of life (HRQoL) predicts long-term survival in patients with peripheral artery disease (PAD) independent of established prognostic risk factors. In 2004, data on 711 consecutive patients with PAD undergoing vascular surgery were collected from 11 hospitals in The Netherlands. After 1 year, patients were contacted to complete the EuroQol Questionnaire (EQ-5D), of which 503 complied. HRQoL assessed by the EQ-5D was divided into tertiles (i.e. poor, intermediate and good HRQoL). Mortality was subsequently assessed 3 years after surgery. Of the 503 patients, 55 (11%) patients died during follow-up. Mortality was 21% in patients with poor HRQoL, 8% in patients with intermediate HRQoL, and 5% in patients with good HRQoL. Patients with poor HRQoL (HR = 5.4; 95% CI 2.3-12.5) had a worse survival compared to patients with a good HRQoL, after adjusting for established prognostic factors. In conclusion, the study indicates that poor HRQoL predicts long-term survival in patients with PAD, and provides prognostic value above established risk factors.
引用
收藏
页码：163 / 169
页数：7
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