Synthesis, characterization and toxicity of new heterobimetallic complexes of platinum(II) and palladium(II)

Heterobimetallic complexes of the type [M(C6H6N2)(2)(M')(2)(R)(4)]Cl-2 have been synthesized by the direct reaction of [M(C6H8N2)(2)]Cl-2 with Group 4 or 14 organometallic dichlorides Ph2M'Cl-2,Me2M'Cl-2 or Cp2M"Cl-2 in 1:2 molar ratio in MeOH (M = Pd or Pt, M' = Si or Sn and M" = Ti or Zr), The compounds were characterized by elemental analysis, molecular weight determination, electronic, H-1 NMR and IR spectra, magnetic susceptibilities and conductivity measurements, These studies showed that the compounds are monomers and dimagnetic in nature, with a square-planar geometry around palladium and platinum metals. Both the free ligands and their metal complexes were screened for antimicrobial activity on different species of pathogenic fungi and bacteria and were found active in this respect. Copyright (C) 2001 John Wiley & Sons, Ltd.