Treatment of Locally Advanced Pancreatic Ductal Adenocarcinoma

被引：10
|
作者：
Loehrer, Andrew P. [1 ]
Ferrone, Cristina R. [1 ]
机构：
[1] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA
来源：
DIGESTIVE SURGERY | 2016年 / 33卷 / 04期
关键词：
Pancreas cancer; Chemotherapy; Radiotherapy; Chemoradiation; Combined modality therapy; INTRAOPERATIVE RADIATION-THERAPY; LONG-TERM OUTCOMES; NEOADJUVANT CHEMORADIATION; ADJUVANT CHEMORADIATION; SURGICAL RESECTION; VASCULAR RESECTION; PLUS RADIOTHERAPY; IMPROVED SURVIVAL; BEAM IRRADIATION; NAB-PACLITAXEL;
D O I：
10.1159/000445020
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Pancreatic ductal adenocarcinoma (PDAC) is increasingly common and a leading cause of cancer-related mortality. Surgery remains the only possibility for cure. Upwards of 40% of patients present with locally advanced PDAC (LA-PDAC), where management strategies continue to evolve. In this review, we highlight current trends in neoadjuvant chemotherapy, surgical resection, and other multimodality approaches for patients with LA-PDAC. Despite promising early results, additional work is needed to more accurately and appropriately tailor treatment for patients with LA-PDAC. (C) 2016 S. Karger AG, Basel
引用
收藏
页码：343 / 350
页数：8
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