Smart therapeutic-polymer-loaded silica nanomaterials. Nanomedicine

Need for materials with high biocompatible properties have led to the development of porous silica nanoparticles. The structure of present nanostructures consists of a core and a silica shell or the silica core is coated with organic shell. The composite nanoparticles coated by organic shells with functional groups were considered to govern the covalent immobilization of biomolecules. The nanoparticles with unique chemical and physical properties may be useful as biosensors in living whole cells. The enhanced cellular drug delivery to cancer cell lines via nanoconjugates revealed that smart nanoparticles are an effective tool for transporting and delivering drugs.