Objectives: To evaluate the independent association between alcohol consumption and risk of developing psoriasis and to determine if this risk is associated with different types of alcoholic beverages. Design: A prospective study of female nurses who were followed up from 1991 to 2005. Setting: Nurses' Health Study II, a cohort of 116 671 US women aged 27 to 44 years in 1991. Participants: The study population included 82 869 women who reported amount and type of alcohol intake on biennial questionnaires. We excluded participants with a history of psoriasis prior to 1991. Main Outcome Measure: Self-report of incident physician-diagnosed psoriasis. For a sensitivity analysis, we had a subset of confirmed psoriasis cases. Results: There were 1150 cases of incident psoriasis, 1069 of which were used for analysis. Compared with women who did not drink alcohol, the multivariate relative risk (RR) of psoriasis was 1.72 (95% confidence interval [CI], 1.15-2.57) for an alcohol consumption of 2.3 drinks/wk or more. When examined by type of alcoholic beverage, there was an association between psoriasis and nonlight beer intake (multivariate RR for >= 5 drinks/wk, 1.76; 95% CI, 1.15-2.69); light beer, red wine, white wine, and liquor were not significantly associated with psoriasis risk. The association with nonlight beer intake became stronger in a subset of confirmed psoriasis cases (multivariate RR for >= 5 drinks/wk, 2.29; 95% CI, 1.36-3.85). Conclusions: Nonlight beer intake is associated with an increased risk of developing psoriasis among women. Other alcoholic beverages did not increase the risk of psoriasis in this study.
机构:
Brigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA USA
Brown Univ, Dept Dermatol, Warren Alpert Med Sch, Providence, RI 02903 USABrigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
Wu, Shaowei
Cho, Eunyoung
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Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA USA
Brown Univ, Dept Dermatol, Warren Alpert Med Sch, Providence, RI 02903 USABrigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
Cho, Eunyoung
Li, Wen-Qing
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Harvard Univ, Sch Med, Boston, MA USABrigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
Li, Wen-Qing
Han, Jiali
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机构:
Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA USA
Indiana Univ, Dept Epidemiol, Richard M Fairbanks Sch Publ Hlth, Melvin & Bren Simon Canc Ctr, Indianapolis, IN 46204 USA
Indiana Univ, Dept Dermatol, Sch Med, Indianapolis, IN 46204 USABrigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
Han, Jiali
Qureshi, Abrar A.
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机构:
Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA USA
Brown Univ, Dept Dermatol, Warren Alpert Med Sch, Providence, RI 02903 USABrigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
机构:
Shandong Univ, Dept Epidemiol, Sch Publ Hlth, Jinan, Shandong, Peoples R ChinaShandong Univ, Dept Epidemiol, Sch Publ Hlth, Jinan, Shandong, Peoples R China
Li, Suyun
Cho, Eunyoung
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Brown Univ, Dept Dermatol, Warren Alpert Med Sch, 339 Eddy St, Providence, RI 02903 USA
Brown Univ, Dept Epidemiol, Sch Publ Hlth, Providence, RI 02912 USA
Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA USAShandong Univ, Dept Epidemiol, Sch Publ Hlth, Jinan, Shandong, Peoples R China
Cho, Eunyoung
Drucker, Aaron M.
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机构:
Brown Univ, Dept Dermatol, Warren Alpert Med Sch, 339 Eddy St, Providence, RI 02903 USAShandong Univ, Dept Epidemiol, Sch Publ Hlth, Jinan, Shandong, Peoples R China
Drucker, Aaron M.
Qureshi, Abrar A.
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h-index: 0
机构:
Brown Univ, Dept Dermatol, Warren Alpert Med Sch, 339 Eddy St, Providence, RI 02903 USA
Brown Univ, Dept Epidemiol, Sch Publ Hlth, Providence, RI 02912 USA
Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA USAShandong Univ, Dept Epidemiol, Sch Publ Hlth, Jinan, Shandong, Peoples R China
Qureshi, Abrar A.
Li, Wen-Qing
论文数: 0引用数: 0
h-index: 0
机构:
Brown Univ, Dept Dermatol, Warren Alpert Med Sch, 339 Eddy St, Providence, RI 02903 USA
Brown Univ, Dept Epidemiol, Sch Publ Hlth, Providence, RI 02912 USAShandong Univ, Dept Epidemiol, Sch Publ Hlth, Jinan, Shandong, Peoples R China