Distinct regions of the cytoplasmic domain of c-mpl mediate TPO-induced Akt, Bad, and p110 Ser/Thr phosphorylation and apoptosis.

被引：0

|

作者：

Yang, J

Ritchey, J

Korsmeyer, S

Bray, P

DiPersio, JF

机构：

[1] Washington Univ, Sch Med, Div Bone Marrow Transplantat, St Louis, MO 63110 USA

[2] Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA

来源：

BLOOD | 1998年 / 92卷 / 10期

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D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

251

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页码：63A / 63A

页数：1

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共 3 条

[1] Y626 of C-MPL is critical for TPO-induced SHIP/SHC tyrosine phosphorylation, phosph-AKT, and p110 tyrosine phosphorylation and expression.
Yang, J
Ritchey, J
Haug, J
Holt, M
DiPersio, J
BLOOD, 1999, 94 (10) : 47A - 47A
[2] AKT activation, p110 expression, SHC/SHIP and anti-apoptosis signaling events map to distinct regions of c-mpl.
Yang, JNA
Vij, RA
DiPersio, JF
BLOOD, 2000, 96 (11) : 74A - 74A
[3] DISTINCT REGIONS OF C-MPL CYTOPLASMIC DOMAIN ARE COUPLED TO THE JAK-STAT SIGNAL-TRANSDUCTION PATHWAY AND SHC PHOSPHORYLATION
GURNEY, AL
WONG, SC
HENZEL, WJ
DESAUVAGE, FJ
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (12) : 5292 - 5296