Formation of periodic nanostructures using a femtosecond laser to control cell spreading on titanium

被引：52

作者：

Shinonaga, T. ^{[1
]}

Tsukamoto, M. ^{[1
]}

Kawa, T. ^{[2
]}

Chen, P. ^{[3
]}

Nagai, A. ^{[3
]}

Hanawa, T. ^{[3
]}

机构：

[1] Osaka Univ, Joining & Welding Res Inst, Osaka 5670047, Japan

[2] Osaka Univ, Grad Sch Engn, Suita, Osaka 5650871, Japan

[3] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Chiyoda Ku, Tokyo 1010062, Japan

来源：

APPLIED PHYSICS B-LASERS AND OPTICS | 2015年 / 119卷 / 03期

关键词：

PROLIFERATION; MORPHOLOGY; ALIGNMENT; ADHESION; SURFACES;

D O I：

10.1007/s00340-015-6082-4

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Although titanium (Ti) is a common biomaterial, controlling cell spreading by forming periodic structures using a femtosecond laser should improve its biocompatibility. Herein we investigate the influence of periodic nanostructures formed on the surface of a Ti plate on cell spreading. Nanostructures with a periodicity of 590 nm are formed using a femtosecond laser with a wavelength of 775 nm. Cell spreading on the plate without period structures lacks a definite direction, whereas cell spreading on the Ti plate with periodic structures occurs along the grooves, suggesting that forming periodic structures via a femtosecond laser can control cell spreading.

引用

页码：493 / 496

页数：4

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