Effect of the properties of organic solvents and water content on the enzymatic synthesis of derivatives of dipeptides containing D-amino acid residue

被引：0

作者：

Shen, HY ^{[1
]}

Tian, GL ^{[1
]}

Yan, AX ^{[1
]}

Jia, Y ^{[1
]}

Hong, YY ^{[1
]}

Ye, YH ^{[1
]}

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Minist Educ, Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

ACTA CHIMICA SINICA | 2003年 / 61卷 / 07期

关键词：

enzymatic reaction; organic solvent; water content; D-amino acid; protease;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The effect of organic solvents and water content on the enzymatic synthesis of protected oligopeptides and its derivatives is very remarkable. The influence of the properties of organic solvents and water content in different organic solvents on the enzymatic synthesis of derivatives of dipeptides containing D-amino acid residue was systemically studied. alpha-Chymotrypsin, subtilisin and thermolysin were used as catalyst for the synthesis of a series of protected dipeptides and its derivatives; furthermore, the effect of water content on the enzymatic reactions was also studied.

引用

页码：1144 / 1148

页数：5

共 16 条

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