Visualizing glycans on single cells and tissues-Visualizing glycans on single cells and tissues

被引：10
|
作者：
Ovryn, Ben [1 ]
Li, Jie [1 ]
Hong, Senlian [1 ]
Wu, Peng [1 ]
机构：
[1] Scripps Res Inst, Dept Mol Med, 10550 N Torrey Pines Rd, La Jolla, CA 92037 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2017年 / 39卷
关键词：
GLYCOSYLATION IN-VIVO; FREE CLICK CHEMISTRY; BIOORTHOGONAL CHEMISTRY; SURFACE GLYCOPROTEINS; LIVE CELLS; BIOCONJUGATION; ZEBRAFISH; CANCER; PROBES;
D O I：
10.1016/j.cbpa.2017.04.018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Metabolic oligosaccharide engineering and chemoenzymatic glycan labeling have provided powerful tools to study glycans in living systems and tissue samples. In this review article, we summarize recent advances in this field with a focus on innovative approaches for glycan imaging. The presented applications demonstrate that several of the leading imaging methods, which have revolutionized quantitative cell biology, can be adapted to imaging glycans on single cells and tissues.
引用
收藏
页码：39 / 45
页数：7
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