Organ-specific chemical differences in Glycosmis trichanthera

被引:19
|
作者
Vajrodaya, S
Bacher, M
Greger, H
Hofer, O
机构
[1] Univ Vienna, Inst Bot, Comparat Phytochem Dept, A-1030 Vienna, Austria
[2] Univ Vienna, Inst Organ Chem, A-1090 Vienna, Austria
[3] Kasetsart Univ, Fac Sci, Dept Bot, Bangkok 10900, Thailand
基金
奥地利科学基金会;
关键词
Glycosmis trichanthera; Rutaceae-Aurantioideae; amides; sulphones; acridones; quinolines; diprenyl indoles; organ-specific differences;
D O I
10.1016/S0031-9422(97)00986-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The lipophilic leaf, stem and root extracts of Glycosmis trichanthera are characterized by distinct chemical profiles, containing sulphur-containing amides in the leaves, prenylated acridone alkaloids in the stem bark, and quinoline alkaloids together with a 3,7-diprenylated indole in the root bark. Two isomeric sulphones derived from methylhio-propenoic acid phenethylamides, named trichanthin-A and -B, and the 3,7-diprenylated indole proved to be new natural products. Structure elucidation of the new compounds is described by spectroscopic evidence. Bioautographic tests with Cladosporium herbarum showed only moderate antifungal activity for trichanthin-B and methylgerambullin. (C) 1998 Elsevier Science Ltd.All rights reserved.
引用
收藏
页码:897 / 902
页数:6
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