COVID-19 in recent kidney transplant recipients

被引:22
|
作者
Shingare, Ashay [1 ]
Bahadur, Madan M. [1 ]
Raina, Shailesh [2 ]
机构
[1] Jaslok Hosp & Res Ctr, Dept Nephrol & Transplantat, Mumbai, Maharashtra, India
[2] Jaslok Hosp & Res Ctr, Dept Urol & Transplant Surg, Mumbai, Maharashtra, India
关键词
clinical research; practice; complication; infectious; immunosuppressive regimens; infection and infectious agents - viral; infectious disease; kidney transplantation; nephrology;
D O I
10.1111/ajt.16120
中图分类号
R61 [外科手术学];
学科分类号
摘要
As the coronavirus disease 2019 (COVID-19) pandemic spread across the globe, transplant programs suffered a setback. We report the first experience of COVID-19 infection within 1 month of living donor kidney transplant (LDKT). We describe 2 LDKT recipients who were detected positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at day 19 and day 7 posttransplant. They had minimal symptoms at diagnosis and did not develop any respiratory complications or allograft dysfunction. Immunosuppression was de-escalated; however, nasopharyngeal swab real-time reverse transcription polymerase chain reaction (rRT-PCR) remained positive for SARS-CoV-2 for a prolonged time. Younger age, absence of other comorbidities, and lower dose of anti-thymocyte globulin (ATG) used as induction possibly contributed to good outcome in our recent LDKT recipients compared with earlier published cases of recent deceased donor kidney transplant recipients with COVID-19.
引用
收藏
页码:3206 / 3209
页数:4
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