Classification of acute myocardial ischemia by artificial neural network using echocardiographic strain waveforms

被引:5
|
作者
McMahon, Eileen M. [1 ]
Korinek, Josef [2 ]
Yoshifuku, Shiro [2 ]
Sengupta, Partho P. [1 ]
Manduca, Armando [2 ]
Belohlavek, Marek [1 ]
机构
[1] Mayo Clin, Coll Med, Scottsdale, AZ 85259 USA
[2] Mayo Clin, Coll Med, Rochester, MN 55905 USA
基金
美国国家卫生研究院;
关键词
strain echocardiography; artificial neural network; acute myocardial ischemia;
D O I
10.1016/j.compbiomed.2008.01.003
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Echocardiographic strain waveforms are highly variable, so their interpretation is experience-dependent and subjective. We tested whether an artificial neural network (ANN) can distinguish between strain waveforms obtained at baseline and during experimentally induced acute ischemia. An open-chest model of coronary occlusion and acute ischemia was used in 14 adult pigs. Strain waveforms were obtained using a GE Vivid 7 ultrasound system. An ANN design was implemented in MATLAB (R), and backpropagation and "leave-one-out" processes were used to train and test it. Specificity of 86% and sensitivity of 87% suggest that ANNs could aid in diagnostic prescreening of echocardiographic strain waveforms. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:416 / 424
页数:9
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