Effects of Peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on Hormonal Activity and Structure of the Thyroid Gland in Hypophysectomized Young Chickens and Old Hens

被引：0

作者：

Kuznik, B. I. ^{[1
]}

Pateyuk, A. V. ^{[1
]}

Rusaeva, N. S. ^{[1
]}

Baranchugova, L. M. ^{[1
]}

Obydenko, V. I. ^{[1
]}

机构：

[1] Chita State Med Acad, Chita, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2011年 / 150卷 / 04期

关键词：

pituitary gland; peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly; thyroid gland; hormones; GROWTH-HORMONE;

D O I：

10.1007/s10517-011-1177-3

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Hypophysectomy in 5-days chickens and old hens was followed by hormonal disturbances and structural changes in the thyroid gland. Administration of peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly synthesized on the basis the amino acid composition of extracts from the anterior and posterior lobes of the pituitary gland, respectively, to hypophysectomized birds for 40 days significantly reduced the degree of these changes. The normalizing effect of synthetic peptides on the concentration of thyrotrophic hormone and thyroid hormones in old hens was less pronounced than in chickens.

引用

页码：495 / 499

页数：5

共 22 条

[1] Effects of Peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on Hormonal Activity and Structure of the Thyroid Gland in Hypophysectomized Young Chickens and Old Hens
B. I. Kuznik
A. V. Pateyuk
N. S. Rusaeva
L. M. Baranchugova
V. I. Obydenko
[J]. Bulletin of Experimental Biology and Medicine, 2011, 150 : 495 - 499
[2] Effect of tetrapeptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on the structure and function of the thyroid gland in neonatally hypophysectomized chickens
Kuznik, B. I.
Pateyuk, A. V.
Rusaeva, N. S.
[J]. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2008, 145 (01) : 104 - 107
[3] Effect of tetrapeptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on the structure and function of the thyroid gland in neonatally hypophysectomized chickens
B. I. Kuznik
A. V. Pateyuk
N. S. Rusaeva
[J]. Bulletin of Experimental Biology and Medicine, 2008, 145 : 104 - 107
[4] Effect of Peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on the Morphology of the Thymus in Hypophysectomized Young and Old Birds
A. V. Pateyk
L. M. Baranchugova
N. S. Rusaeva
V. I. Obydenko
B. I. Kuznik
[J]. Bulletin of Experimental Biology and Medicine, 2013, 154 : 681 - 685
[5] Effect of Peptides Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly on the Morphology of the Thymus in Hypophysectomized Young and Old Birds
Pateyk, A. V.
Baranchugova, L. M.
Rusaeva, N. S.
Obydenko, V. I.
Kuznik, B. I.
[J]. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2013, 154 (05) : 681 - 685
[6] The effect of Lys-Glu-Asp-Gly and Ala-Glu-Asp-Gly peptides on hormone activity and the thyroid structure in sexually mature and old hypophysectomized birds
Kuznik B.I.
Pateyuk A.V.
Rusaeva N.S.
Baranchugova L.M.
Obydenko V.I.
[J]. Advances in Gerontology, 2011, 1 (4) : 340 - 345
[7] Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly) on melatonin secretion by the pineal gland of young and old rats
Y. Djeridane
V. Kh. Khavinson
V. N. Anisimov
Yvan Touitou
[J]. Journal of Endocrinological Investigation, 2003, 26 : 211 - 215
[8] Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly) on melatonin secretion by the pineal gland of young and old rats
Djeridane, Y
Khavinson, VK
Anisimov, VN
Touitou, Y
[J]. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2003, 26 (03) : 211 - 215
[9] PEPTIDES .30. SYNTHESIS OF DECAPEPTIDE LEU-ALA-ALA-GLY-LYS-VAL-GLU-ASP-SER-ASP
AGARWAL, KL
KENNER, GW
SHEPPARD, RC
[J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1969, (16): : 2218 - &
[10] Normalization of Epigenetic Change in the Genome by Peptide Bioregulator (Ala-Glu-Asp-Gly) in Pulmonary Tuberculosis
Lezhava, Teimuraz
Buadze, Tamar
Jokhadze, Tinatin
Monaselidze, Jamlet
Gaiozishvili, Maia
Rubanovi, Ketevan
Kiria, Nana
[J]. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2019, 25 (02) : 555 - 563

← 1 2 3 →