Reduction of side effects by combining clozapine with amisulpride: Case report and short review of clozapine-induced hypersalivation - A case report

被引：27
|
作者：
Croissant, B [1 ]
Hermann, D [1 ]
Olbrich, R [1 ]
机构：
[1] Univ Heidelberg, Cent Inst Mental Hlth, Dept Addict Behav & Addict Med, D-68159 Mannheim, Germany
来源：
PHARMACOPSYCHIATRY | 2005年 / 38卷 / 01期
关键词：
D O I：
10.1055/s-2005-837771
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Side effects from a high-dose clozapine treatment for a schizophrenic patient led to massive compliance problems. The dose of clozapine could be halved without recurrence of an acute psychotic symptomatology by concomitantly administering amisulpride. The side effects, especially hypersalivation, disappeared almost entirely, which in turn led to good compliance. In a short review we would like to present the pathophysiology and therapeutic options of clozapine-induced hypersalivation.
引用
收藏
页码：38 / 39
页数：2
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