This study is concerned with the development of an information system for disaster risk reduction and management in the Philippines. It covered relational and multi-dimensional database designs as well as software applications for disaster preparedness and response combined with Decision Support System. The application highlights the following administrative modules namely community registration with fingerprint biometrics and camera integration, emergency evacuation, search and rescue operation, cash and in-kind donation, evacuation center and disaster event profiling, weather forecast, and private messaging. Moreover, the decision support system highlights the live data consolidation of disaster affected areas and individuals through data visualization and geographic information system. It presents historical information of previous disasters in a multi-dimensional viewpoint from national level to barangay or district level. Finally, the system can dynamically generate predicted list of potential evacuees via Logistic Regression Analysis. The system's response time test revealed a highly acceptable result with latency ranging from 31ms to 419ms. The software quality evaluation in terms of functionality, usability, efficiency, and maintainability proved to be excellent and is highly commendable by the ICT department and operations group of the National Disaster Risk Reduction and Management Council, Office of Civil Defense.