SIRT1: Role in cardiovascular biology

被引：43

作者：

Ma, Lina ^{[1
]}

Li, Yun ^{[1
]}

机构：

[1] Capital Med Univ, Xuan Wu Hosp, Dept Geriatr, Beijing 100053, Peoples R China

来源：

CLINICA CHIMICA ACTA | 2015年 / 440卷

关键词：

SIRT1; Senescence; Cardiovascular biology; Expression regulation; ACTIVATED PROTEIN-KINASE; SMALL-MOLECULE ACTIVATORS; MYOCARDIAL GLUCOSE-UPTAKE; CARDIAC-HYPERTROPHY; METABOLIC SYNDROME; DEACETYLASE SIRT1; OXIDATIVE STRESS; MITOCHONDRIAL-FUNCTION; HISTONE DEACETYLASE; CELLULAR SENESCENCE;

D O I：

10.1016/j.cca.2014.10.036

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

SIRT1 (silent information regulator two protein) is a type III protein deacetylase that regulates a variety of important metabolic and physiologic processes including stress resistance, metabolism, apoptosis and energy balance. It-reverses cholesterol transport and reduces risk for development of atherosclerosis and cardiovascular disease. The following review highlights the potential role of SIRT1 on cardiovascular biology and function. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：8 / 15

页数：8

共 50 条

[1] SIRT1 in cardiovascular aging
Luo, Xin-Yuan
Qu, Shun-Lin
Tang, Zhi-Han
Zhang, Yuan
Liu, Mi-Hua
Peng, Juan
Tang, Hui
Yu, Kang-Lun
Zhang, Chi
Ren, Zhong
Jiang, Zhi-Sheng
[J]. CLINICA CHIMICA ACTA, 2014, 437 : 106 - 114
[2] The Role of SirT1 in Reproduction
Rickert, Emily
Webster, Nicholas
[J]. BIOLOGY OF REPRODUCTION, 2011, 85
[3] The Role of Sirt1 in Epileptogenesis
Hall, Alicia M.
Brennan, Gary P.
Nguyen, Tiffany M.
Singh-Taylor, Akanksha
Mun, Hyun-Seung
Sargious, Mary J.
Baram, Tallie Z.
[J]. ENEURO, 2017, 4 (01)
[4] Adverse childhood events and cardiovascular diseases: the potential role of Sirt1
Rodriguez-Miguelez, Paula
Pollock, Jennifer S.
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2021, 321 (03): : H577 - H579
[5] The role of Sirt1 in tumorigenesis
Ren, Natalie Shunxiang
[J]. CANCER RESEARCH, 2015, 75
[6] The sirtuin family members SIRT1, SIRT3 and SIRT6: Their role in vascular biology and atherogenesis
Sosnowska, Bozena
Mazidi, Mohsen
Penson, Peter
Gluba-Brzozka, Anna
Rysz, Jacek
Banach, Maciej
[J]. ATHEROSCLEROSIS, 2017, 265 : 275 - 282
[7] SIRT1 as a regulator of cardiovascular oxidative stress
Xia, N.
Daiber, A.
Habermeier, A.
Spanier, G.
Lu, Q.
Oelze, M.
Closs, E., I
Muenzel, T.
Foerstermann, U.
Li, H.
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2009, 379 : 21 - 22
[8] The role of SIRT1 in kidney diseases
Wang, Wei
Hu, Yuanyuan
Ding, Ning
Wei, Jiping
Li, Cairong
[J]. INTERNATIONAL UROLOGY AND NEPHROLOGY, 2024,
[9] Role of SIRT1 in homologous recombination
Uhl, Miriam
Csernok, Andreea
Aydin, Sevtap
Kreienberg, Rolf
Wiesmueller, Lisa
Gatz, Susanne Andrea
[J]. DNA REPAIR, 2010, 9 (04) : 383 - 393
[10] Role of SIRT1 in Chemoresistant Leukemia
Fajardo-Orduna, Guadalupe Rosario
Ledesma-Martinez, Edgar
Aguiniga-Sanchez, Itzen
Weiss-Steider, Benny
Santiago-Osorio, Edelmiro
Wiemer, Erik A. C.
Camacho-Arroyo, Ignacio
Melendez-Zajgla, Jorge
Valverde Ramirez, Mahara A.
Rodriguez-Dorantes, Mauricio
[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (19)

← 1 2 3 4 5 →