Disease Free Margins Assessment Using Enhanced Methylene Blue Video Contact Endoscopy with SPIES Filters in Vocal Fold Malignancies

被引：0

作者：

Hainarosie, Razvan ^{[1
,2
]}

Zainea, Viorel ^{[1
,2
]}

Hainarosie, Mura ^{[1
]}

Pietrosanu, Catalina ^{[1
]}

Ionita, Irina ^{[1
]}

机构：

[1] Carol Davila Univ Med & Pharm, 8th Eroii Sanitari Blvd, Bucharest 050474, Romania

[2] Prof Dr D Hociota Inst Phonoaudiol & Funct ENT Su, 21st Mihail Cioranu Str, Bucharest 050751, Romania

来源：

REVISTA DE CHIMIE | 2017年 / 68卷 / 08期

关键词：

methylene blue; vocal fold carcinoma; contact endoscopy; SPIES filters; disease free; GROWTH-FACTOR EXPRESSION; CANCER; LARYNX;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Vocal fold carcinomas represent a pathology that has an important incidence. Recent studies showed that 70% of the dysplastic lesions can skip the phases of mild and severe dysplasia directly to carcinoma. For that reason early detection of a malignancy of the vocal fold is mandatory. If the lesion is discovered in an early stage it must be aggressively treated using CO2 LASER surgery and disease free margins must be obtained. Because frozen sections are not always available in all medical centers we are proposing a new protocol to assess disease free margins during CO2 LASER assisted laryngoscopy. Methylene blue contact endoscopy is not a new method, as it was introduced in laryngology by professors Oscar Diaz and Mario Andreea in 1994. We are proposing a protocol designed to assess disease free margins using an enhanced video contact endoscopy with SPIES software filters. The SPIES filters technology is a relatively new technology proposed by Karl Storz in 2013. A critical analysis of the method will be done comparing the results with paraffin histopathology exam.

引用

页码：1768 / 1770

页数：3