A novel HLA-A allele, HLA-A*02:544

被引:0
|
作者
Zhu, X. [1 ]
Yang, T. [1 ]
Tan, R. [1 ]
Su, P. [1 ]
Luo, Z. [1 ]
Zhen, X. [1 ]
机构
[1] Peking Univ, Dept Obstet & Gynecol, Hosp 3, Beijing 100191, Peoples R China
来源
TISSUE ANTIGENS | 2015年 / 85卷 / 06期
关键词
human leukocyte antigen A*02:544; novel allele; polymerase chain reaction sequence-based typing;
D O I
10.1111/tan.12560
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The novel allele HLA-A*02:544 has two nucleotide changes from its most closely related allele, HLA-A*02:148. Firstly at nucleotide 255 where CT (codon 60 GACGAT), resulting in a non-coding change as GAC and GAT both code for the same amino acid aspartic acid. Secondly at nucleotide 368 where TG (codon 98 TTTTGT) resulting in a coding change, 98 phenylalanine is changed to cysteine.
引用
收藏
页码:501 / 502
页数:2
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