An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines

被引：2
|
作者：
Tian, Haiying [1 ]
Li, Ruiyan [1 ]
Guo, Fang [2 ]
Chen, Xiuling [2 ]
机构：
[1] Changzhi Med Coll, Dept Pharm, Changzhi 046000, Peoples R China
[2] Jinzhong Univ, Dept Mat Sci & Engn, Jinzhong 030619, Peoples R China
来源：
CHEMISTRYOPEN | 2022年 / 11卷 / 08期
关键词：
sulfonamides; sodium sulfinates; NH4I; green protocols; metal-free; BORONIC ACIDS; CATALYZED AMINOSULFONYLATION; BIOLOGICAL-ACTIVITY; SULFONYL AZIDES; SULFUR-DIOXIDE; N-ARYLATION; METAL; DABSO; INHIBITORS; ANALOGS;
D O I：
10.1002/open.202200097
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Sulfonamides have a special role on medicine due to their broad biological activities, as bacterial infections, diabetes mellitus, oedema, hypertension prevention and treatment. In addition, sulfonamides are also useful in herbicides and pesticides. Herein, we communicate an efficient strategy for the preparation of sulfonamides via NH4I-mediated amination of sodium sulfinates. This new method provides a general and environmentally friendly access to sulfonamide compounds and tolerates a wide range of functional groups.
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页数：4
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