Two new compounds from an endophytic fungus Aspergillus sp HS-05

被引：3

作者：

Zhang, Lin ^{[1
,2
]}

Chen, Gang ^{[1
,2
]}

Wu, Hong-Hua ^{[1
,2
]}

Lu, Xuan ^{[1
,2
]}

Pei, Yue-Hu ^{[1
,2
]}

Wu, Xin ^{[3
]}

Pan, Bo ^{[1
]}

Hua, Hui-Ming ^{[1
,2
]}

Bai, Jiao ^{[1
,2
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China

[2] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China

[3] Shenyang Pharmaceut Univ, Sch Life Sci & Biopharmaceut, Shenyang 110016, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2011年 / 13卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Aspergillus sp; endophytic fungus; structure elucidation; anticancer activity;

D O I：

10.1080/10286020.2010.550885

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new compounds, N-[4'-hydroxy-(E)-cinnamoyl]-l-tyrosine methyl ester (1) and methyl 4-methoxy-3-(3'-hydroxy-2'-methyl)propionyloxy-benzoate (2), were isolated from EtOAc extract of the fermentation broth of the endophytic fungus Aspergillus sp. HS-05. Their structures were elucidated by NMR, IR, UV, MS, and CD methods. Compounds 1 and 2 showed no anticancer activities against HL-60 cell lines (both of IC50100M) in vitro.

引用

页码：225 / 229

页数：5

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