Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.

被引：8

作者：

Nesterova, Yu. V. ^{[1
]}

Povet'eva, T. N. ^{[1
]}

Zibareva, L. N. ^{[2
]}

Suslov, N. I. ^{[1
,2
]}

Zueva, E. P. ^{[1
]}

Aksinenko, S. G. ^{[1
]}

Afanas'eva, O. G. ^{[1
]}

Krylova, S. G. ^{[1
]}

Amosova, E. N. ^{[1
]}

Rybalkina, O. Yu. ^{[1
,2
]}

Lopatina, K. A. ^{[1
,2
]}

机构：

[1] Tomsk Natl Res Med Ctr, ED Goldberg Res Inst Pharmacol & Regenerat Med, Tomsk, Russia

[2] Natl Res Tomsk State Univ, Tomsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2017年 / 163卷 / 02期

关键词：

anti-inflammatory and analgesic activities; flavonoids; SUBSTANCES;

D O I：

10.1007/s10517-017-3771-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Anti-inflammatory and analgesic activities of the complex of flavonoids from Lychnis chalcedonica L.were studied in the models of acute aseptic inflammation induced by carrageenan, histamine, and serotonin and acetic acid- induced painful chemical stimulation. It is demonstrated that course treatment with flavonoids derived from Lychnis chalcedonica L. produced a stable pharmacological effect comparable with that of the reference anti-inflammatory drug diclofenac.

引用

页码：222 / 225

页数：4

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