The JAK inhibitor INCB20 induces antiproliferative and apoptotic effects in human myeloma cells in vitro and in vivo

被引：0
|
作者：
Burger, R
Legouill, S
Tai, YT
Shringarpure, R
Podar, K
Catley, L
Tassone, P
Neri, P
Hideshima, T
Chauhan, D
Caulder, E
Vaddi, K
Neilan, CL
Gramatzki, M
Fridman, JS
Anderson, KC
机构：
[1] Univ Kiel, Dept Med 2, Div Stem Cell Transplantat & Immunotherapy, D-24098 Kiel, Germany
[2] Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA USA
[3] Incyte Corp, Wilmington, DE USA
来源：
BLOOD | 2005年 / 106卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
3357
引用
收藏
页码：938A / 938A
页数：1
相关论文
共 50 条
  • [1] Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo
    Burger, Renate
    Le Gouill, Steven
    Tai, Yu-Tzu
    Shringarpure, Reshma
    Tassone, Pierfrancesco
    Neri, Paola
    Podar, Klaus
    Catley, Laurence
    Hideshinl, Teru
    Chauhan, Dharminder
    Caulder, Eian
    Neilan, Claire L.
    Vaddi, Kris
    Li, Jun
    Gramatzki, Martin
    Fridman, Jordan S.
    Anderson, Kenneth C.
    [J]. MOLECULAR CANCER THERAPEUTICS, 2009, 8 (01) : 26 - 35
  • [2] Zoledronate exerts direct antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo
    Guenther, A
    Gordon, S
    Bakker, F
    Burger, R
    Tiemann, M
    Green, JR
    Rogers, M
    Gramatzki, M
    [J]. BLOOD, 2005, 106 (11) : 946A - 946A
  • [3] Effects of INCB052793, a Selective JAK1 Inhibitor, in Combination with Anti- Myeloma Agents on Human Multiple Myeloma (MM) In Vitro and In Vivo
    Sanchez, Eric
    Li, Mingjie
    Wang, Cathy S.
    Mehta, Puja
    Tang, George
    Chen, Haiming
    Berenson, James
    [J]. BLOOD, 2016, 128 (22)
  • [4] Anti-Myeloma Effects of the Selective JAK1 Inhibitor INCB052793 in Combination with Active Myeloma Agents In Vitro and In Vivo
    Sanchez, Eric
    Porter, Autumn
    Li, Mingjie
    Wang, Cathy
    Smith, Emily
    Soof, Camilia
    Director, Chelsea
    Tang, George
    Chen, Haiming
    Berenson, James
    [J]. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2017, 17 (01): : E49 - E50
  • [5] The anti-myeloma effects of the selective JAK1 inhibitor (INCB052793) alone and in combination in vitro and in vivo
    Sanchez, Eric
    Li, Mingjie
    Patil, Saurabh
    Soof, Camilia M.
    Nosrati, Jason D.
    Schlossberg, Remy E.
    Vidisheva, Aleksandra
    Tanenbaum, Edward J.
    Hekmati, Tara
    Zahab, Brian
    Wang, Cathy
    Tang, George
    Chen, Haiming
    Berenson, James R.
    [J]. ANNALS OF HEMATOLOGY, 2019, 98 (03) : 691 - 703
  • [6] The anti-myeloma effects of the selective JAK1 inhibitor (INCB052793) alone and in combination in vitro and in vivo
    Eric Sanchez
    Mingjie Li
    Saurabh Patil
    Camilia M. Soof
    Jason D. Nosrati
    Remy E. Schlossberg
    Aleksandra Vidisheva
    Edward J. Tanenbaum
    Tara Hekmati
    Brian Zahab
    Cathy Wang
    George Tang
    Haiming Chen
    James R. Berenson
    [J]. Annals of Hematology, 2019, 98 : 691 - 703
  • [7] Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro
    P Tassone
    P Tagliaferri
    C Viscomi
    C Palmieri
    M Caraglia
    A D'Alessandro
    E Galea
    A Goel
    A Abbruzzese
    C R Boland
    S Venuta
    [J]. British Journal of Cancer, 2003, 88 : 1971 - 1978
  • [8] Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro
    Tassone, P
    Tagliaferri, P
    Viscomi, C
    Palmieri, C
    Caraglia, M
    D'Alessandro, A
    Galea, E
    Goel, A
    Abbruzzese, A
    Boland, CR
    Venuta, S
    [J]. BRITISH JOURNAL OF CANCER, 2003, 88 (12) : 1971 - 1978
  • [9] In vitro apoptotic and antiproliferative effects of propranolol on human breast cancer cells
    Alizade, Ares
    Terzi, Menderes Yusuf
    [J]. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2024, 62 (05) : 326 - 331
  • [10] In vitro and in vivo antiproliferative effects of simvastatin, an HMG-CoA reductase inhibitor, on human glioma cells
    Tetsuro Kikuchi
    Yasufumi Nagata
    Toshiaki Abe
    [J]. Journal of Neuro-Oncology, 1997, 34 : 233 - 239
12345