Synthesis of 5-aminolevulinic acid (ALA) and its t-butyl ester for the fluorescence detection of early cancer

被引：6
|
作者：
Kang, MS
Kim, DM
Kim, JS
Jeong, JH [1 ]
机构：
[1] Kyung Hee Univ, Coll Pharm, Seoul 130701, South Korea
[2] PDT Bio Co Ltd, Seoul 130701, South Korea
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2005年 / 28卷 / 10期
关键词：
5-aminolevulinic acid; fluorescence detection; ALA; PDT;
D O I：
10.1007/BF02972970
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.
引用
收藏
页码：1111 / 1113
页数：3
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