Born to RUNX1

被引:1
|
作者
Sung, Pamela J. [1 ]
Babushok, Daria V. [1 ,2 ]
机构
[1] Univ Penn, Philadelphia, PA 19104 USA
[2] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
关键词
D O I
10.1182/blood.2020006152
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this issue of Blood, Simon et al evaluated 430 samples from patients with acute myeloid leukemia (AML) for germline and somatic mutations in RUNX family transcription factor 1 (RUNX1). They found that nearly 30% of the identified variants were germline.(1)
引用
收藏
页码:1824 / 1825
页数:2
相关论文
共 50 条
  • [1] RUNX1 and cancer
    Lin, Tsung-Chieh
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2022, 1877 (03):
  • [2] Free RUNX1
    Grant Miura
    Nature Chemical Biology, 2015, 11 (4) : 241 - 241
  • [3] RUNX1 Expression Can be Complementary to RUNX1 Mutation in MDS Prognostication
    Wang, Yu-Hung
    Yao, Chi-Yuan
    Lin, Chien-Chin
    Hsu, Chia-Lang
    Hou, Hsin-An
    Tien, Hwei-Fang
    Chou, Wen-Chien
    BLOOD, 2021, 138
  • [4] Novel RUNX1 targeted therapy for AML expressing mutant RUNX1
    Mill, Christopher P.
    DiNardo, Courtney D.
    Fiskus, Warren
    Saenz, Dyana T.
    Nowak, Agnieszka J.
    Sun, Baohua
    Saenz, David N.
    Kornblau, Steven M.
    Bhalla, Kapil N.
    CANCER RESEARCH, 2018, 78 (13)
  • [5] SCL and RUNX1 regulate RUNX1 gene expression by association to RUNX1-P1 promoter
    Gutierrez, S.
    Martinez, M.
    FEBS JOURNAL, 2014, 281 : 689 - 689
  • [6] Transcription factor RUNX1
    E. N. Markova
    N. V. Petrova
    S. V. Razin
    O. L. Kantidze
    Molecular Biology, 2012, 46 : 755 - 767
  • [7] RUNX1 as a recombinase cofactor
    Cieslak, Agata
    Payet-Bornet, Dominique
    Asnafi, Vahid
    ONCOTARGET, 2015, 6 (26) : 21793 - 21794
  • [8] Runx1 blocks elongation
    不详
    NATURE IMMUNOLOGY, 2006, 7 (01) : 17 - 17
  • [9] RUNX1-RUNX1 homodimerization modulates RUNX1 activity and function
    Li, Donglan
    Sinha, Kislay K.
    Hay, Maher A.
    Rinaldi, Ciro R.
    Saunthararajah, Yogen
    Nucifora, Giuseppina
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (18) : 13542 - 13551
  • [10] Chromatin regulation by RUNX1
    Lichtinger, Monika
    Hoogenkamp, Maarten
    Krysinska, Hanna
    Ingram, Richard
    Bonifer, Constanze
    BLOOD CELLS MOLECULES AND DISEASES, 2010, 44 (04) : 287 - 290