Polymer translocation out of planar confinements

被引:51
|
作者
Panja, Debabrata [1 ]
Barkema, Gerard T. [2 ,3 ]
Ball, Robin C. [4 ]
机构
[1] Univ Amsterdam, Inst Theoret Phys, NL-1018 XE Amsterdam, Netherlands
[2] Univ Utrecht, Inst Theoret Phys, NL-3584 CE Utrecht, Netherlands
[3] Leiden Univ, Inst Lorentz, NL-2333 CA Leiden, Netherlands
[4] Univ Warwick, Dept Phys, Coventry CV4 7AL, W Midlands, England
关键词
D O I
10.1088/0953-8984/20/7/075101
中图分类号
O469 [凝聚态物理学];
学科分类号
070205 ;
摘要
Polymer translocation in three dimensions out of planar confinements is studied in this paper. Three membranes are located at z = -h, z = 0 and z = h(1). These membranes are impenetrable, except for the middle one at z = 0, which has a narrow pore. A polymer with length N is initially sandwiched between the membranes placed at z = -h and z = 0 and translocates through this pore. We consider strong confinement (small h), where the polymer is essentially reduced to a two-dimensional polymer, with a radius of gyration scaling as R-g((2D)) similar to N-nu 2D; here, nu(2D) = 0.75 is the Flory exponent in two dimensions. The polymer performs Rouse dynamics. On the basis of theoretical analysis and high-precision simulation data, we show that in the unbiased case h = h(1), the dwell time tau(d) scales as N2+nu 2D, in perfect agreement with our previously published theoretical framework. For h(1) = infinity, the situation is equivalent to field-driven translocation in two dimensions. We show that in this case tau(d) scales as N-2 nu 2D, in agreement with several existing numerical results in the literature. This result violates the earlier reported lower bound N1+nu for tau(d) for field-driven translocation. We argue, on the basis of energy conservation, that the actual lower bound for tau(d) is N-2 nu and not N1+nu. Polymer translocation in such theoretically motivated geometries thus resolves some of the most fundamental issues that have been the subject of much heated debate in recent times.
引用
收藏
页数:9
相关论文
共 50 条
  • [1] Polymer translocation into and out of an ellipsoidal cavity
    Polson, James M.
    JOURNAL OF CHEMICAL PHYSICS, 2015, 142 (17):
  • [2] Polymer translocation out of confined environments
    Luo, Kaifu
    Metzler, Ralf
    Ala-Nissila, Tapio
    Ying, See-Chen
    PHYSICAL REVIEW E, 2009, 80 (02)
  • [3] Polymer chain dynamics under nanoscopic confinements
    Kimmich, R
    Fatkullin, N
    Mattea, C
    Fischer, E
    MAGNETIC RESONANCE IMAGING, 2005, 23 (02) : 191 - 196
  • [4] Mechanics of Semiflexible Polymer Chains Under Confinements
    Wang, J.
    Li, R.
    SIXTH INTERNATIONAL CONFERENCE ON NONLINEAR MECHANICS (ICNM-VI), 2013, : 133 - 136
  • [5] End-Pulled Translocation of a Star Polymer Out of a Confining Cylindrical Cavity
    Tilahun, Mesay
    Tatek, Yergou B.
    MACROMOLECULAR THEORY AND SIMULATIONS, 2021, 30 (02)
  • [6] Polymer Translocation
    Lu-Wei Lu
    Zhen-Hua Wang
    An-Chang Shi
    Yu-Yuan Lu
    Li-Jia An
    ChineseJournalofPolymerScience, 2023, 41 (05) : 683 - 698
  • [7] Polymer translocation
    Muthukumar, Murugappan
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2013, 31 : 133 - 133
  • [8] Polymer Translocation
    Lu, Lu-Wei
    Wang, Zhen-Hua
    Shi, An-Chang
    Lu, Yu-Yuan
    An, Li-Jia
    CHINESE JOURNAL OF POLYMER SCIENCE, 2023, 41 (05) : 683 - 698
  • [9] Polymer Translocation
    Lu-Wei Lu
    Zhen-Hua Wang
    An-Chang Shi
    Yu-Yuan Lu
    Li-Jia An
    Chinese Journal of Polymer Science, 2023, 41 : 683 - 698
  • [10] Protein translocation - In or out?
    Cunliffe, L
    NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (03) : 192 - 193