Substance use disorders and suicidality in youth: A systematic review and meta-analysis with a focus on the direction of the association

被引:24
|
作者
Rioux, Charlie [1 ]
Huet, Anne-Sophie [2 ]
Castellanos-Ryan, Natalie [3 ,4 ]
Fortier, Laurianne [4 ]
Le Blanc, Myriam [5 ,6 ]
Hamaoui, Stephanie [7 ]
Geoffroy, Marie-Claude [8 ,9 ,10 ]
Renaud, Johanne [9 ,10 ,11 ]
Seguin, Jean R. [4 ,5 ]
机构
[1] Texas Tech Univ, Dept Educ Psychol & Leadership, Lubbock, TX 79409 USA
[2] Univ Ottawa, Dept Child & Adolescent Psychiat, Ottawa, ON, Canada
[3] Univ Montreal, Sch Psychoeducat, Montreal, PQ H2W 1R7, Canada
[4] CHU Ste Justine Res Ctr, Montreal, PQ, Canada
[5] Univ Montreal, Dept Psychiat & Addictol, Montreal, PQ, Canada
[6] Inst Natl Psychiat Legale Philippe Pine, Montreal, PQ, Canada
[7] Univ Quebec Montreal, Dept Psychol, Montreal, PQ, Canada
[8] McGill Univ, Dept Educ & Counselling Psychol, Montreal, PQ, Canada
[9] McGill Univ, Dept Psychiat, Montreal, PQ, Canada
[10] Douglas Mental Hlth Univ Inst, McGill Grp Suicide Studies, Montreal, PQ, Canada
[11] Manulife Ctr Breakthroughs Teen Depress & Suicide, Montreal, PQ, Canada
来源
PLOS ONE | 2021年 / 16卷 / 08期
基金
加拿大健康研究院;
关键词
MENTAL-HEALTH; ALCOHOL-USE; GENDER-DIFFERENCES; COPING SKILLS; YOUNG-ADULTS; RISK-FACTORS; CANNABIS USE; HONG-KONG; DRUG-USE; IDEATION;
D O I
10.1371/journal.pone.0255799
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Reviews and meta-analyses suggest that substance use and suicidality (i.e., suicidal ideations and attempts) are associated in youth, but the direction of this association remains unclear. Theoretically, the secondary psychiatric disorder hypothesis (SPDH) posits that substance use leads to suicidality, while the secondary substance use disorder hypothesis (SSUDH) posits that suicidality leads to substance use. To clarify these associations, this meta-analysis systematically reviewed studies that examined the prospective associations between SUDs and suicidality in youth (age 25 and younger) and compared results according to the direction of the association. Methods Web of Science, Embase, PsycINFO, PubMed, Medline and ProQuest Dissertations & Theses Global were searched from inception to March 8, 2020, and 55 effect sizes from 23 samples were included and analyzed using a three-level meta-analysis. Results SUDs significantly predicted subsequent suicidality (OR = 2.16, 95%CI 1.57-2.97), suicidality significantly predicted subsequent SUDs (OR = 2.16, 95%CI 1.53-3.04), and these effect sizes did not differ (p = 0.49). Conclusions Considering that 65% of reviewed studies only examined the SPDH, this review highlights that more attention should be given to the SSUDH, and that studies should examine bidirectional associations between SUDs and suicidality across time. Clinically, because SUDs and suicidality were found to influence each other, results suggest that mental health and SUDs should ideally be detected and treated early, and that co-occurring disorders should be assessed and treated concomitantly.
引用
收藏
页数:20
相关论文
共 50 条
  • [1] Suicidality in autistic youth: A systematic review and meta-analysis
    O'Halloran, L.
    Coey, P.
    Wilson, C.
    [J]. CLINICAL PSYCHOLOGY REVIEW, 2022, 93
  • [2] The association of telomere length with substance use disorders: systematic review and meta-analysis protocol
    Navarro-Mateu, Fernando
    Rubio-Aparicio, Maria
    Cayuela, Pedro
    Alvarez, Francisco-Javier
    Roca-Vega, Agustin
    Dolores Chirlaque, Maria
    Luisa Cayuela, Maria
    Husky, Mathilde
    Martinez, Salvador
    Sanchez-Meca, Julio
    [J]. SYSTEMATIC REVIEWS, 2019, 8 (01)
  • [3] The association of telomere length with substance use disorders: systematic review and meta-analysis protocol
    Fernando Navarro-Mateu
    María Rubio-Aparicio
    Pedro Cayuela
    Francisco-Javier Álvarez
    Agustín Roca-Vega
    María Dolores Chirlaque
    María Luisa Cayuela
    Mathilde Husky
    Salvador Martínez
    Julio Sánchez-Meca
    [J]. Systematic Reviews, 8
  • [4] Acupuncture for substance use disorders: meta-analysis A systematic review and
    Grant, Sean
    Kandrack, Ryan
    Motala, Aneesa
    Shanman, Roberta
    Booth, Marika
    Miles, Jeremy
    Sorbero, Melony
    Hempel, Susanne
    [J]. DRUG AND ALCOHOL DEPENDENCE, 2016, 163 : 1 - 15
  • [5] Social Anxiety and Suicidality in Youth: A Systematic Review and Meta-analysis
    Leigh, Eleanor
    Chiu, Kenny
    Ballard, Elizabeth D. D.
    [J]. RESEARCH ON CHILD AND ADOLESCENT PSYCHOPATHOLOGY, 2023, 51 (04): : 441 - 454
  • [6] Social Anxiety and Suicidality in Youth: A Systematic Review and Meta-analysis
    Eleanor Leigh
    Kenny Chiu
    Elizabeth D. Ballard
    [J]. Research on Child and Adolescent Psychopathology, 2023, 51 : 441 - 454
  • [7] The association of telomere length with substance use disorders: a systematic review and meta-analysis of observational studies
    Navarro-Mateu, Fernando
    Husky, Mathilde
    Cayuela-Fuentes, Pedro
    Alvarez, Francisco-Javier
    Roca-Vega, Agustin
    Rubio-Aparicio, Maria
    Dolores Chirlaque, Maria
    Luisa Cayuela, Maria
    Martinez, Salvador
    Sanchez-Meca, Julio
    [J]. ADDICTION, 2021, 116 (08) : 1954 - 1972
  • [8] A systematic review and meta-analysis of neuromodulation therapies for substance use disorders
    Mehta, Dhvani D.
    Praecht, Angela
    Ward, Heather B.
    Sanches, Marcos
    Sorkhou, Maryam
    Tang, Victor M.
    Steele, Vaughn R.
    Hanlon, Colleen A.
    George, Tony P.
    [J]. NEUROPSYCHOPHARMACOLOGY, 2024, 49 (04) : 649 - 680
  • [9] A systematic review and meta-analysis of neuromodulation therapies for substance use disorders
    Dhvani D. Mehta
    Angela Praecht
    Heather B. Ward
    Marcos Sanches
    Maryam Sorkhou
    Victor M. Tang
    Vaughn R. Steele
    Colleen A. Hanlon
    Tony P. George
    [J]. Neuropsychopharmacology, 2024, 49 : 649 - 680
  • [10] Emotion regulation in substance use disorders: a systematic review and meta-analysis
    Stellern, Jordan
    Xiao, Ke Bin
    Grennell, Erin
    Sanches, Marcos
    Gowin, Joshua L.
    Sloan, Matthew E.
    [J]. ADDICTION, 2023, 118 (01) : 30 - 47