Epithelioid leiomyosarcoma of the uterine cervix

Background. Leiomyosarcomas with an epithelioid appearance arising in the uterine cervix are extremely rare neoplasms. We present a case of triple uterine cancer containing cervical epithelloid leiomyosarcoma. Case. A 72-year-old Japanese woman, gravida 1, para 1, 55 years in menopause, visited her local doctor due to atypical bleeding and the endometrial smear was suspect for malignancy. She was referred to our hospital. Endometrial curettage revealed endometrioid adenocarcinoma, G1, with a fragment of sarcomatous tumor. A total hysterectomy with bilateral salpingo-oophorectomy was performed. The histological findings revealed triple uterine cancer consisting of endometrial adenocarcinoma, cervical epithelioid leiomyosarcoma, and cervical squamous cell carcinoma. Conclusion. This extremely rare case of triple uterine cancer containing cervical epithelioid leiomyosarcoma is the first report, to the best of our knowledge. (C) 2001 Academic Press.