The Role of Angiogenesis in Neuroendocrine Tumors

被引：5
|
作者：
Lyons, John, III [1 ]
Anthony, Catherine T. [1 ]
Woltering, Eugene A. [1 ]
机构：
[1] Louisiana State Univ, Hlth Sci Ctr, Dept Surg, New Orleans, LA 70112 USA
来源：
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2010年 / 39卷 / 04期
关键词：
Angiogenesis; i-MTOR inhibitors; Vascular endothelial growth factor (VEGF); Platelet-derived growth factor (PDGF); Human in vitro modeling; Somatostatin receptors; METASTATIC CARCINOID-TUMORS; PHASE-II; SOMATOSTATIN ANALOG; IN-VITRO; INHIBITS ANGIOGENESIS; OCTREOTIDE; GROWTH; 2-METHOXYESTRADIOL; CELLS; ASSAY;
D O I：
10.1016/j.ecl.2010.08.006
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The first studies to assess in vitro angiogenesis in neuroendocrine tumors used animal-based assays to study the antiangiogenic properties of somatostatin analogs. Current technologies enable investigators to directly appraise the in vitro angiogenic response of an individual's neuroendocrine tumor with and without potential antiangiogenic reagents. This article describes the evolution of methods to assess in vitro angiogenesis in neuroendocrine tumors and describes some of the clinical data.
引用
收藏
页码：839 / +
页数：15
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