Progressive multifocal leukoencephalopathy in a lung transplant recipient

被引:18
|
作者
Shitrit, D
Nirit, L
Shiran, SI
Izbicki, G
Sofer, D
Eldad, M
Kramer, MR
机构
[1] Rabin Med Ctr, Pulm Inst, IL-49100 Petah Tiqwa, Israel
[2] Rabin Med Ctr, Dept Neurol, IL-49100 Petah Tiqwa, Israel
[3] Rabin Med Ctr, Dept Radiol, IL-49100 Petah Tiqwa, Israel
[4] Sackler Sch Med, Tel Aviv, Israel
[5] Hadassah Med Ctr, Dept Pathol, IL-91120 Jerusalem, Israel
来源
关键词
D O I
10.1016/S1053-2498(02)00804-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Progressive multifocal leukoencephalopathy (PML) is a sub-acute, demyelinating disease of the brain caused by a human polyomavirus. We describe a patient with the onset of PML 7 months after lung transplantation. The patient was treated with immunosuppressive modulation and cidofovir, a new anti-viral therapy for PML, with stabilization of the symptoms. We also review the 4 additional reports in the literature of PML after heart and lung transplantation. Progressive multifocal leukoencephalopathy may become more prevalent as the population of heart and lung transplantation recipients increases.
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收藏
页码:946 / 950
页数:5
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