STI-571, a selective tyrosine kinase inhibitor, significantly enhances antigen presentation by bone marrow derived APCs: Implications for immunotherapy of tumors-derived from antigen presenting cells.

被引：0
|
作者：
Wang, HW [1 ]
Cheng, FD [1 ]
Cuenca, AG [1 ]
Bhalla, K [1 ]
Sotomayor, EM [1 ]
机构：
[1] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Dept Oncol, Tampa, FL 33612 USA
来源：
BLOOD | 2001年 / 98卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
55
引用
收藏
页码：16A / 16A
页数：1
相关论文
共 4 条
  • [1] Inhibition of c-kit signaling in antigen-presenting cells (APCs) by the tyrosine kinase inhibitor STI-571, enhances the priming of naive T-cells and restores the responsiveness of anergic T cells from tumor bearing hosts.
    Wang, HW
    Cheng, FD
    Cuenca, AG
    Bhalla, K
    Sotomayor, EM
    BLOOD, 2002, 100 (11) : 370A - 370A
  • [2] Antigen presentation and immune regulatory capacity of immature and mature-enriched antigen presenting (Dendritic) cells derived from human bone marrow
    Jin, Y
    Fuller, L
    Ciancio, G
    Burke, GW
    Tzakis, AG
    Ricordi, C
    Miller, J
    Esquenzai, V
    HUMAN IMMUNOLOGY, 2004, 65 (02) : 93 - 103
  • [3] Cross-presentation of tumor antigens by bone marrow derived antigen-presenting cells (APCs) is the dominant mechanism in tolerance induction to B-cell lymphomas.
    Sotomayor, EM
    Borrello, I
    Rattis, FM
    Abrams, J
    Levitsky, HI
    BLOOD, 1999, 94 (10) : 629A - 629A
  • [4] IL-2 linked to a peptide from influenza hemagglutinin enhances T cell activation by affecting the antigen-presentation function of bone marrow-derived dendritic cells
    Faulkner, L
    Buchan, G
    Lockhart, E
    Slobbe, L
    Wilson, M
    Baird, M
    INTERNATIONAL IMMUNOLOGY, 2001, 13 (06) : 713 - 721
1