Evaluating 3D-Printed Biomaterials as Scaffolds for Vascularized Bone Tissue Engineering

被引：221

作者：

Wang, Martha O. ^{[1
]}

Vorwald, Charlotte E. ^{[1
]}

Dreher, Maureen L. ^{[2
]}

Mott, Eric J. ^{[3
]}

Cheng, Ming-Huei ^{[4
]}

Cinar, Ali ^{[5
]}

Mehdizadeh, Hamidreza ^{[5
]}

Somo, Sami ^{[6
]}

Dean, David ^{[3
]}

Brey, Eric M. ^{[6
,7
]}

Fisher, John P. ^{[1
]}

机构：

[1] Univ Maryland, Fischell Dept Bioengn, College Pk, MD 20742 USA

[2] US FDA, Div Solid & Fluid Mech, Off Sci & Engn Labs, Ctr Devices & Radiol Hlth, Silver Spring, MD USA

[3] Ohio State Univ, Dept Plast Surg, Columbus, OH 43210 USA

[4] Chang Gung Univ, Chang Gung Mem Hosp, Dept Plast & Reconstruct Surg, Div Reconstruct Microsurg,Coll Med, Taoyuan, Taiwan

[5] IIT, Dept Chem & Biol Engn, Chicago, IL 60616 USA

[6] IIT, Dept Biomed Engn, Chicago, IL 60616 USA

[7] Hines VA Hosp, Res Serv, Hines, IL USA

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 01期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

OSTEOGENIC SIGNAL EXPRESSION; IN-VITRO DEGRADATION; POLY(PROPYLENE FUMARATE); CROSS-LINKING; DESIGN; NEOVASCULARIZATION; DIFFERENTIATION; HYDROXYAPATITE; ANGIOGENESIS; POROSITY;

D O I：

10.1002/adma.201403943

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented).There is an unmet need for a consistent set of tools for the evaluation of 3Dprinted constructs. A toolbox developed to design, characterize, and evaluate 3Dprinted poly(propylene fumarate) scaffolds is proposed for vascularized engineered tissues. This toolbox combines modular design and nondestructive fabricated design evaluation, evaluates biocompatibility and mechanical properties, and models angiogenesis. © 2014 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：138 / 144

页数：7

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