Pregnancy achieved by transfer of a single blastocyst selected by time-lapse monitoring

被引:82
|
作者
Pribenszky, Csaba [1 ]
Matyas, Szabolcs [2 ]
Kovacs, Peter [2 ]
Losonczi, Eszter [3 ]
Zadori, Janos [4 ]
Vajta, Gabor [5 ]
机构
[1] Szent Istvan Univ, Dept Anim Breeding & Genet, Fac Vet Sci, H-1078 Budapest, Hungary
[2] KAALI Inst Budapest, H-1125 Budapest, Hungary
[3] ARTech Co Res & Dev, Debrecen, Hungary
[4] Univ Szeged, Ctr Assisted Reprod, Kaali Inst, H-6725 Budapest, Hungary
[5] Beijing Genom Inst Shenzhen, Shenzhen, Peoples R China
关键词
early cleavage; fragmentation; single-embryo transfer; time-lapse monitoring; EMBRYO DEVELOPMENT; IN-VITRO; FRAGMENTATION; FERTILIZATION; EMBRYOGENESIS; FIELDS;
D O I
10.1016/j.rbmo.2010.04.015
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Appropriate selection of a single blastocyst for transfer decreases the risk of multiple gestations. By using a compact time-lapse microscope system placed inside a regular incubator, combined with a microwell embryo culture dish, the development of all the embryos from a patient was continuously monitored by obtaining images at 10 min intervals. The embryos were not moved during the time-lapse observation. The system was switched off completely between image acquisitions in order to avoid exposure to electromagnetic radiation. The analysis of time-lapse records was used to choose a single blastocyst for transfer, which resulted in a singleton pregnancy and birth of a healthy boy on term. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:533 / 536
页数:4
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