Rapid prototyping of multilayer thiolene microfluidic chips by photopolymerization and transfer lamination

被引：36
|
作者：
Natali, Marco [1 ]
Begolo, Stefano [2 ]
Carofiglio, T. [3 ]
Mistura, Giampaolo [2 ]
机构：
[1] CNR, ICIS, Corso Stati Uniti 4, I-35127 Padua, Italy
[2] Univ Padua, Dept Phys, I-35131 Padua, Italy
[3] Univ Padua, Dept Chem, I-35131 Padua, Italy
来源：
LAB ON A CHIP | 2008年 / 8卷 / 03期
关键词：
D O I：
10.1039/b716594c
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A new fabrication process is described allowing rapid prototyping of multilayer microfluidic chips using commercial thiolene optical adhesives. Thiolene monomer liquid is photopolymerized across transparency masks to obtain partially cured patterns supported on thin polyethylene sheets. The patterns are easily laminated and transferred to a substrate due to the elastomeric nature and adhesiveness of partially cured thiolene. The process characteristics are evaluated by realizing several test structures and fluidic chips. As an example of application, the operation of a microfluidic bead array sensor for pH measurements is then described in some detail.
引用
收藏
页码：492 / 494
页数：3
相关论文
共 50 条
  • [1] Rapid prototyping of glass microfluidic chips
    Kotz, Frederik
    Plewa, Klaus
    Bauer, Werner
    Hanemann, Thomas
    Waldbaur, Ansgar
    Wilhelm, Elisabeth
    Neumann, Christiane
    Rapp, Bastian E.
    [J]. MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS XIII, 2015, 9320
  • [2] Rapid prototyping of microfluidic chips in COC
    Steigert, J.
    Haeberle, S.
    Brenner, T.
    Mueller, C.
    Steinert, C. P.
    Koltay, P.
    Gottschlich, N.
    Reinecke, H.
    Ruehe, J.
    Zengerle, R.
    Ducree, J.
    [J]. JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2007, 17 (02) : 333 - 341
  • [3] Simple photolithographic rapid prototyping of microfluidic chips
    Hoyland, James
    Kunstmann-Olsen, Casper
    Rubahn, Horst-Gunter
    [J]. MICROELECTRONIC ENGINEERING, 2012, 98 : 689 - 692
  • [4] Rapid Prototyping of Multilayer Thermoplastic Microfluidic Chip
    Yang, Tianhang
    Su, Ye
    Li, Songjing
    [J]. PROCEEDINGS OF 2015 INTERNATIONAL CONFERENCE ON FLUID POWER AND MECHATRONICS - FPM 2015, 2015, : 706 - 710
  • [5] Ultra rapid prototyping of microfluidic systems using liquid phase photopolymerization
    Khoury, C
    Mensing, GA
    Beebe, DJ
    [J]. LAB ON A CHIP, 2002, 2 (01): : 50 - 55
  • [6] Rapid prototyping of microfluidic chips enabling controlled biotechnology applications in microspace
    Garmasukis, Rokas
    Hackl, Claudia
    Charvat, Ales
    Mayr, Stefan G.
    Abel, Bernd
    [J]. CURRENT OPINION IN BIOTECHNOLOGY, 2023, 81
  • [7] Lamination-based rapid prototyping of microfluidic devices using flexible thermoplastic substrates
    Paul, Debjani
    Pallandre, Antoine
    Miserere, Sandrine
    Weber, Jeremie
    Viovy, Jean-Louis
    [J]. ELECTROPHORESIS, 2007, 28 (07) : 1115 - 1122
  • [8] Study of Lamination Characteristics for Rapid Prototyping
    Liu Yu
    Zhang Hanbi
    E Maohua (Huazhong University of Science and Technoloyg Dept . Optoelectronic Engineering
    [J]. Chinese Journal of Lasers, 1996, (02) : 145 - 149
  • [9] Rapid prototyping of PMMA microfluidic chips utilizing a CO2 laser
    Ting-Fu Hong
    Wei-Jhong Ju
    Ming-Chang Wu
    Chang-Hsien Tai
    Chien-Hsiung Tsai
    Lung-Ming Fu
    [J]. Microfluidics and Nanofluidics, 2010, 9 : 1125 - 1133
  • [10] Rapid prototyping of microfluidic chips for dead-volume-free MS coupling
    Claudia Dietze
    Tobias Scholl
    Stefan Ohla
    Johannes Appun
    Christoph Schneider
    Detlev Belder
    [J]. Analytical and Bioanalytical Chemistry, 2015, 407 : 8735 - 8743
12345