Threshold dynamics and optimal control on an age-structured SIRS epidemic model with vaccination

被引:0
|
作者
Ma, Han [1 ]
Zhang, Qimin [1 ]
机构
[1] Ningxia Univ, Sch Math & Stat, Yinchuan 750021, Ningxia, Peoples R China
关键词
SIRS epidemic model; age-structure; threshold dynamics; optional control; Hamilton-Jacobi-Bellman (HJB) equation; STABILITY ANALYSIS; GLOBAL STABILITY;
D O I
10.3934/mbe.2021465
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We consider a vaccination control into a age-structured susceptible-infective-recovered-susceptible (SIRS) model and study the global stability of the endemic equilibrium by the iterative method. The basic reproduction number R-0 is obtained. It is shown that if R-0 < 1, then the disease-free equilibrium is globally asymptotically stable, if R-0 > 1, then the disease-free and endemic equilibrium coexist simultaneously, and the global asymptotic stability of endemic equilibrium is also shown. Additionally, the Hamilton-Jacobi-Bellman (HJB) equation is given by employing the Bellman's principle of optimality. Through proving the existence of viscosity solution for HJB equation, we obtain the optimal vaccination control strategy. Finally, numerical simulations are performed to illustrate the corresponding analytical results.
引用
收藏
页码:9474 / 9495
页数:22
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