Toward the multi-scale simulation for a human body using the next-generation supercomputer

被引：2

作者：

Matsumoto, Yoichiro ^{[1
]}

Ii, Satoshi ^{[2
]}

Shiozaki, Seiji ^{[3
]}

Sugiyama, Kazuyasu ^{[1
,3
]}

Takagi, Shu ^{[1
,3
]}

机构：

[1] Univ Tokyo, Sch Engn, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138656, Japan

[2] Osaka Univ, Dept Mech Sci & Bioengn, Toyonaka, Osaka 5600043, Japan

[3] RIKEN, Computat Sci Res, Wako, Saitama 3510198, Japan

来源：

MECHANICS FOR THE WORLD: PROCEEDINGS OF THE 23RD INTERNATIONAL CONGRESS OF THEORETICAL AND APPLIED MECHANICS, ICTAM2012 | 2014年 / 10卷

关键词：

Eulerian method; fluid-structure interaction; blood flow; stochastic Monte Carlo method; FLUID-STRUCTURE INTERACTION; SIMPLE SHEAR-FLOW; EULERIAN APPROACH; DEFORMATION; BOUNDARIES; PLATELETS; CAPSULES; BINDING; VOLUME;

D O I：

10.1016/j.piutam.2014.01.018

中图分类号：

TH [机械、仪表工业];

学科分类号：

0802 ;

摘要：

We have developed novel numerical methods for fluid-structure and fluid-membrane interaction problems. The basic equation set is formulated in a full Eulerian framework. The method is based on the finite difference volume-of-fluid scheme with fractional step algorithm. It is validated through a numerical solution to a deformable vesicle problem, and applied to blood flows including red blood cells (RBCs) and platelets. Further, to gain insight into the mechanism of thrombus formation, a stochastic Monte Carlo model to describe the platelet-vessel wall interaction is incorporated into the Eulerian method. The effect of the RBCs on the platelet motion is discussed. (C) 2013 Published by Elsevier Ltd.

引用

页码：193 / 200

页数：8

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