Relationship between Abortion and Breast Cancer on the Basis of Meta-Analysis

The relationship between abortion and breast cancer among Chinese women were studied in this paper. Articles that ware about risk factors of female breast cancer were searched through Chinese journals full-text database and VIP Chinese science and technology journals full-text database from 1989 to 2005. The identified papers were analyzed using Meta-analysis in order to assess the comprehensive relation between abortion and female breast cancer. Six case-control studies were selected. The cumulative cases and controls were 1440 and 1785. Significant heterogeneity was detected among the 6 studies (Q=17.03, P<0.05). Combined estimate of OR of ever exposure to induced abortion for random effect model was 2.04 (95% confidence interval (CI): 1.50-2.76). This meta-analysis suggests a possible weak association between induced abortion and female breast cancer. The women who exposured to induced abortion and miscarrage would have higher risk of being breast cancer than non-exposure to induced abortion and miscarrage.