A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

被引:233
|
作者
Klionsky, Daniel J. [1 ,2 ,3 ]
Baehrecke, Eric H. [4 ]
Brumell, John H. [5 ]
Chu, Charleen T. [6 ]
Codogno, Patrice [7 ,8 ]
Cuervo, Ana Maria [9 ]
Debnath, Jayanta [10 ]
Deretic, Vojo [11 ]
Elazar, Zvulun [12 ]
Eskelinen, Eeva-Liisa [13 ]
Finkbeiner, Steven [14 ,15 ,16 ]
Fueyo-Margareto, Juan [17 ]
Gewirtz, David [18 ]
Jaattela, Marja [19 ]
Kroemer, Guido [20 ]
Levine, Beth [21 ,22 ]
Melia, Thomas J. [23 ]
Mizushima, Noboru [24 ]
Rubinsztein, David C. [25 ]
Simonsen, Anne [26 ]
Thorburn, Andrew [27 ]
Thumm, Michael [28 ]
Tooze, Sharon A. [29 ]
机构
[1] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA
[4] Univ Massachusetts, Sch Med, Dept Canc Biol, Worcester, MA USA
[5] Hosp Sick Children, Cell Biol Program, Toronto, ON M5G 1X8, Canada
[6] Univ Pittsburgh, Sch Med, Dept Pathol, Pittsburgh, PA USA
[7] INSERM, U984, Chatenay Malabry, France
[8] Univ Paris 11, Chatenay Malabry, France
[9] Albert Einstein Coll Med, Inst Aging Res, Marion Bessin Liver Res Ctr, Dept Dev & Mol Biol, Bronx, NY 10467 USA
[10] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94140 USA
[11] Univ New Mexico, Hlth Sci Ctr, Dept Mol Genet & Microbiol, Albuquerque, NM 87131 USA
[12] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel
[13] Univ Helsinki, Dept Biosci, Helsinki, Finland
[14] Univ Calif San Francisco, Gladstone Inst Neurol Dis, San Francisco, CA 94143 USA
[15] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
[16] Univ Calif San Francisco, Dept Physiol, San Francisco, CA USA
[17] Univ Texas Houston, MD Anderson Canc Ctr, Dept Neurooncol, Houston, TX 77030 USA
[18] Virginia Commonwealth Univ, Massey Canc Ctr, Richmond, VA USA
[19] Danish Canc Soc, Dept Apoptosis, Copenhagen, Denmark
[20] Univ Paris 05, Fac Med, INSERM, Ctr Rech Cordeliers,U872, Paris, France
[21] Univ Texas SW Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX 75390 USA
[22] Univ Texas SW Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA
[23] Yale Univ, Dept Cell Biol, New Haven, CT USA
[24] Tokyo Med & Dent Univ, Dept Physiol & Cell Biol, Tokyo, Japan
[25] Cambridge Inst Med Res, Dept Med Genet, Cambridge, England
[26] Univ Oslo, Dept Biochem, Inst Basic Med Sci, Oslo 3, Norway
[27] Univ Colorado, Ctr Canc, Dept Pharmacol, Denver, CO 80262 USA
[28] Univ Gottingen, Zentrum Biochem & Mol Zellbiol, Gottingen, Germany
[29] Canc Res UK, London Res Inst, London, England
关键词
autophagy; lysosome; mitophagy; pexophagy; stress; vacuole; ACTIVATED PROTEIN-KINASE; STARVATION-INDUCED AUTOPHAGY; VACUOLE TARGETING PATHWAY; COILED-COIL PROTEIN; REGULATES AUTOPHAGY; CELL-DEATH; AMINOPEPTIDASE-I; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL; 3-PHOSPHATE; PIECEMEAL MICROAUTOPHAGY;
D O I
10.4161/auto.7.11.17661
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The study of autophagy is rapidly expanding, and our knowledge of the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. The vocabulary associated with autophagy has grown concomitantly. In fact, it is difficult for readers-even those who work in the field-to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors and chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, and the roles of accessory components and structures that are associated with autophagy.
引用
收藏
页码:1273 / 1294
页数:22
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