Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs

被引：53
|
作者：
de Aquino, LPCT [1 ]
Machado, RZ [1 ]
Alessi, AC [1 ]
Marques, LC [1 ]
de Castro, MB [1 ]
MAlheiros, EB [1 ]
机构：
[1] UNESP, Fac Ciencias Agr & Vet, Dept Patol Vet, BR-14870000 Jaboticabal, SP, Brazil
来源：
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 1999年 / 94卷 / 02期
关键词：
Trypanosoma evansi; dogs; biometry; Elisa; immunofluorescent antibody test; clinical features;
D O I：
10.1590/S0074-02761999000200025
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
This research investigated the pattern of antibody, response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody, test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia.
引用
收藏
页码：255 / 260
页数：6
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